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ChemicalBook >> CAS DataBase List >> pilaralisib

pilaralisib

pilaralisib price.
  • $72 - $1500
  • Product name: pilaralisib
  • CAS: 934526-89-3
  • MF: C25H25ClN6O4S
  • MW: 541.02
  • EINECS:
  • MDL Number:MFCD26142605
  • Synonyms:PILARALISIB (XL147);SAR245408;XL 147;XL-147,Pilaralisib, SAR245408;XL147(pilaralisib);2-amino-N-[3-[[3-(2-chloro-5-methoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide;2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide;Pilaralisib (XL-147);pilaralisib;Propanamide, 2-amino-N-[3-[[[3-[(2-chloro-5-methoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-2-methyl-
Price32 Properties Safety Information Description
32 prices
Selected condition：
Brand
  • AK Scientific
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 2mg
  • 10mg
  • 250mg
  • 10mM*1mLinDMSO
  • 25mg
  • 10mM*1mLinDMSO(Solution)
  • 5mg
  • 50mg
  • 100mg
  • 1g
  • 10mM*1mLinDMSO(Solid+Solvent)
  • ManufacturerAK Scientific
  • Product number9609BB
  • Product descriptionPilaralisib
  • Packaging1g
  • Price$1060
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-16526
  • Product descriptionPilaralisib 98.81%
  • Packaging50mg
  • Price$285
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-16526
  • Product descriptionPilaralisib 98.81%
  • Packaging100mg
  • Price$456
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-16526
  • Product descriptionPilaralisib 98.81%
  • Packaging5mg
  • Price$72
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-16526
  • Product descriptionPilaralisib 98.81%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$81
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-16526
  • Product descriptionPilaralisib 98.81%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$85
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-16526
  • Product descriptionPilaralisib 98.81%
  • Packaging10mg
  • Price$114
  • Updated2026-05-26
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1222985
  • Product descriptionPilaralisib >98%(HPLC)
  • Packaging2mg
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1222985
  • Product descriptionPilaralisib >98%(HPLC)
  • Packaging5mg
  • Price$110
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1222985
  • Product descriptionPilaralisib >98%(HPLC)
  • Packaging10mg
  • Price$180
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1222985
  • Product descriptionPilaralisib >98%(HPLC)
  • Packaging25mg
  • Price$280
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1222985
  • Product descriptionPilaralisib >98%(HPLC)
  • Packaging100mg
  • Price$560
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1222985
  • Product descriptionPilaralisib >98%(HPLC)
  • Packaging50mg
  • Price$410
  • Updated2026-05-06
  • Buy
  • ManufacturerCayman Chemical
  • Product number18011
  • Product descriptionPilaralisib ≥98%
  • Packaging50mg
  • Price$581
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number18011
  • Product descriptionPilaralisib ≥98%
  • Packaging25mg
  • Price$323
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18011
  • Product descriptionXL147 ≥98%
  • Packaging25mg
  • Price$356
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9609BB Pilaralisib 1g $1060 2021-12-16 Buy
Arctom HY-16526 Pilaralisib 98.81% 50mg $285 2026-05-26 Buy
Arctom HY-16526 Pilaralisib 98.81% 100mg $456 2026-05-26 Buy
Arctom HY-16526 Pilaralisib 98.81% 5mg $72 2026-05-26 Buy
Arctom HY-16526 Pilaralisib 98.81% 10mM*1mLinDMSO(Solid+Solvent) $81 2026-05-26 Buy
Arctom HY-16526 Pilaralisib 98.81% 10mM*1mLinDMSO(Solution) $85 2026-05-26 Buy
Arctom HY-16526 Pilaralisib 98.81% 10mg $114 2026-05-26 Buy
Biorbyt Ltd orb1222985 Pilaralisib >98%(HPLC) 2mg $90 2026-05-06 Buy
Biorbyt Ltd orb1222985 Pilaralisib >98%(HPLC) 5mg $110 2026-05-06 Buy
Biorbyt Ltd orb1222985 Pilaralisib >98%(HPLC) 10mg $180 2026-05-06 Buy
Biorbyt Ltd orb1222985 Pilaralisib >98%(HPLC) 25mg $280 2026-05-06 Buy
Biorbyt Ltd orb1222985 Pilaralisib >98%(HPLC) 100mg $560 2026-05-06 Buy
Biorbyt Ltd orb1222985 Pilaralisib >98%(HPLC) 50mg $410 2026-05-06 Buy
Cayman Chemical 18011 Pilaralisib ≥98% 50mg $581 2023-06-20 Buy
Cayman Chemical 18011 Pilaralisib ≥98% 25mg $323 2024-03-01 Buy
Cayman Chemical 18011 XL147 ≥98% 25mg $356 2026-04-30 Buy
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Properties

Melting point :216-220oC
Density :1.458±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly)
pka :6.33±0.30(Predicted)
form :Solid
color :Light Yellow to Yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. Pilaralisib is a methylbenzenesulfonamide derivative that reversibly inhibits class I PI3Ks (IC50s = 39, 36, 23, and 383 nM for p110α, -δ, -γ, and -β, respectively). It has been shown to abrogate Akt and S6 kinase phosphorylation, reduce cyclin D1 and retinoblastoma protein, and upregulate the CDK inhibitor p27, inhibiting cell proliferation. In HER2-overexpressing breast cancer cells, cotreatment with the HER2 inhibitors trastuzumab or lapatinib are reported to sensitize tumor cells to the growth inhibitory effect of pilaralisib. This compound has been evaluated in clinical trials in patients with advanced solid tumors.

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Suppliers and manufacturers

career henan chemical co
pilaralisib
$1.00 /1g
pilaralisib CAS:934526-89-3
TargetMol Chemicals Inc.
Pilaralisib
$38.00 /2mg
Pilaralisib CAS:934526-89-3
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
PT CHEM GROUP LIMITED
ShenZhen Trendseen Biological Technology Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd