prenylamine
|
- $44 - $1732.5
- Product name: prenylamine
- CAS: 390-64-7
- MF: C24H27N
- MW: 329.47788
- EINECS:206-869-4
- MDL Number:MFCD00242807
- Synonyms:3,3-diphenylpropyl(alpha-methylphenethyl)amine;prenylamine;DL-PrenylaMine;N-(1-Methyl-2-phenylethyl)-γ-phenylbenzenepropanaMine;SAN 13-194;Sandoz 13-194;Segontin;Prenylamine (base and/or unspecified salts)
10 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- TRC
Package
- 5mg
- 10mg
- 25MG
- 50mg
- 100MG
- 500mg
- 1G
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008067
- Product descriptionPRENYLAMINE 95.00%
- Packaging25MG
- Price$367.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008067
- Product descriptionPRENYLAMINE 95.00%
- Packaging100MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008067
- Product descriptionPRENYLAMINE 95.00%
- Packaging1G
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29430
- Product descriptionPrenylamine
- Packaging5mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29430
- Product descriptionPrenylamine
- Packaging10mg
- Price$84
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29430
- Product descriptionPrenylamine
- Packaging50mg
- Price$384
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29430
- Product descriptionPrenylamine
- Packaging100mg
- Price$680
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberP712800
- Product descriptionPrenylamine
- Packaging25mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP712800
- Product descriptionPrenylamine
- Packaging100mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP712800
- Product descriptionPrenylamine
- Packaging500mg
- Price$1455
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0008067 | PRENYLAMINE 95.00% | 25MG | $367.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008067 | PRENYLAMINE 95.00% | 100MG | $721.88 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008067 | PRENYLAMINE 95.00% | 1G | $1732.5 | 2021-12-16 | Buy |
| Cayman Chemical | 29430 | Prenylamine | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 29430 | Prenylamine | 10mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 29430 | Prenylamine | 50mg | $384 | 2024-03-01 | Buy |
| Cayman Chemical | 29430 | Prenylamine | 100mg | $680 | 2024-03-01 | Buy |
| TRC | P712800 | Prenylamine | 25mg | $135 | 2021-12-16 | Buy |
| TRC | P712800 | Prenylamine | 100mg | $350 | 2021-12-16 | Buy |
| TRC | P712800 | Prenylamine | 500mg | $1455 | 2021-12-16 | Buy |
Properties
Melting point :36.5-37.5°
Boiling point :457.06°C (rough estimate)
Density :1.0703 (rough estimate)
refractive index :1.9000 (estimate)
storage temp. :Refrigerator
solubility :Chloroform: slightly soluble; Methanol: slightly soluble
form :A solid
pka :pKa 8.74±0.02(40% EtOH,t =25) (Uncertain)
Water Solubility :50mg/L(37 ºC)
Boiling point :457.06°C (rough estimate)
Density :1.0703 (rough estimate)
refractive index :1.9000 (estimate)
storage temp. :Refrigerator
solubility :Chloroform: slightly soluble; Methanol: slightly soluble
form :A solid
pka :pKa 8.74±0.02(40% EtOH,t =25) (Uncertain)
Water Solubility :50mg/L(37 ºC)
Safety Information
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Description
Prenylamine is a calcium channel inhibitor. It inhibits the plasma membrane Ca2+ ATPase (PMCA) in isolated and purified pig cardiac sarcolemma. It binds to a hydrophobic site on calcium-bound calmodulin (CaM) with a Kd value of 0.5 μM and inhibits CaM-activated cAMP phosphodiesterase (PDE) activity when used at concentrations ranging from 10 to 50 μM, an effect that is negatively associated with the concentration of calmodulin. Prenylamine (30 μM) shortens action potential duration and decreases the amplitude of peak calcium currents in single guinea pig ventricular myocytes in the absence and presence of propranolol and phentolamine . Prenylamine (50 mg/kg) decreases epinephrine, serotonin, and dopamine levels in rat brain. It also decreases epinephrine levels in rat heart. It protects anesthetized rats from coronary artery occlusion-induced arrhythmia when administered at a dose of 0.5 mg/kg but increases mortality due to atrioventricular block leading to asystole when administered at a dose of 5 mg/kg.Related product price
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