α-Naphthoflavone
- $18 - $975
- Product name: α-Naphthoflavone
- CAS: 604-59-1
- MF: C19H12O2
- MW: 272.3
- EINECS:210-071-1
- MDL Number:MFCD00004985
- Synonyms:7,8-BENZOFLAVONE;ALPHA-NAPHTHOFLAVONE;A-NAPHTHOFLAVANONE;A-NAPHTHOFLAVONE;BENZOFLAVONE;NAPHTHOFLAVANONE, A-;NAPHTHOFLAVONE, A-;2-b)pyran-4-one,2-phenyl-4h-naphtho(
37 prices
Selected condition:
Brand
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- TRC
Package
- 10mg
- 20mg
- 100mg
- 1G
- 5g
- 10g
- 25g
- 50g
- 100g
- 250g
- ManufacturerAK Scientific
- Product numberJ54118
- Product description2-Phenyl-4H-benzo[h]chromen-4-one
- Packaging5g
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberA18542
- Product descriptionalpha-Naphthoflavone, 97%
- Packaging5g
- Price$51.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberA18542
- Product descriptionalpha-Naphthoflavone, 97%
- Packaging25g
- Price$215.65
- Updated2024-03-01
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0004616
- Product descriptionALPHA-NAPHTHOFLAVONE 95.00%
- Packaging1G
- Price$430.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0004616
- Product descriptionALPHA-NAPHTHOFLAVONE 95.00%
- Packaging5G
- Price$469.3
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0004616
- Product descriptionALPHA-NAPHTHOFLAVONE 95.00%
- Packaging25G
- Price$746.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3353
- Product descriptionα-Naphthoflavone
- Packaging10g
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR1158
- Product descriptionalpha-Naphthoflavone
- Packaging5g
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR1158
- Product descriptionalpha-Naphthoflavone
- Packaging25g
- Price$279
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR1158
- Product descriptionalpha-Naphthoflavone
- Packaging100g
- Price$595
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN94465
- Product description7,8-Benzoflavone
- Packaging20mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number4501
- Product descriptionalpha-Naphthylflavone
- Packaging10mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number4501
- Product descriptionalpha-Naphthylflavone
- Packaging20mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number4501
- Product descriptionalpha-Naphthylflavone
- Packaging100mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB09432
- Product description7,8-Benzoflavone
- Packaging10g
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB09432
- Product description7,8-Benzoflavone
- Packaging25g
- Price$70
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J54118 | 2-Phenyl-4H-benzo[h]chromen-4-one | 5g | $20 | 2021-12-16 | Buy |
Alfa Aesar | A18542 | alpha-Naphthoflavone, 97% | 5g | $51.65 | 2024-03-01 | Buy |
Alfa Aesar | A18542 | alpha-Naphthoflavone, 97% | 25g | $215.65 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | PXT0004616 | ALPHA-NAPHTHOFLAVONE 95.00% | 1G | $430.2 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PXT0004616 | ALPHA-NAPHTHOFLAVONE 95.00% | 5G | $469.3 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PXT0004616 | ALPHA-NAPHTHOFLAVONE 95.00% | 25G | $746.5 | 2021-12-16 | Buy |
ApexBio Technology | C3353 | α-Naphthoflavone | 10g | $135 | 2021-12-16 | Buy |
Apolloscientific | OR1158 | alpha-Naphthoflavone | 5g | $111 | 2021-12-16 | Buy |
Apolloscientific | OR1158 | alpha-Naphthoflavone | 25g | $279 | 2021-12-16 | Buy |
Apolloscientific | OR1158 | alpha-Naphthoflavone | 100g | $595 | 2021-12-16 | Buy |
Arctom | CFN94465 | 7,8-Benzoflavone | 20mg | $40 | 2021-12-16 | Buy |
AvaChem | 4501 | alpha-Naphthylflavone | 10mg | $29 | 2021-12-16 | Buy |
AvaChem | 4501 | alpha-Naphthylflavone | 20mg | $39 | 2021-12-16 | Buy |
AvaChem | 4501 | alpha-Naphthylflavone | 100mg | $49 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB09432 | 7,8-Benzoflavone | 10g | $40 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB09432 | 7,8-Benzoflavone | 25g | $70 | 2021-12-16 | Buy |
Properties
Melting point :153-157 °C (lit.)
Boiling point :375.35°C (rough estimate)
Density :1.1382 (rough estimate)
refractive index :1.5510 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Crystalline Powder or Crystals
color :yellow
BRN :210862
Stability :Stable. Incompatible with strong oxidizing agents.
LogP :5.003 (est)
CAS DataBase Reference :604-59-1(CAS DataBase Reference)
EPA Substance Registry System :4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl- (604-59-1)
Boiling point :375.35°C (rough estimate)
Density :1.1382 (rough estimate)
refractive index :1.5510 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Crystalline Powder or Crystals
color :yellow
BRN :210862
Stability :Stable. Incompatible with strong oxidizing agents.
LogP :5.003 (est)
CAS DataBase Reference :604-59-1(CAS DataBase Reference)
EPA Substance Registry System :4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl- (604-59-1)
Safety Information
Symbol(GHS): | ||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||
Precautionary statements: |
|
Description
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. α-Naphthoflavone is a flavone that modulates xenobiotic metabolism at several points. It antagonizes AhR, blocking the expression of phase I and II genes at nanomolar concentrations, although it can agonize AhR at higher concentrations (10 μM). α-Naphthoflavone inhibits CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50s = 500, 60, 6, and 5 nM, respectively), whereas it activates CYP3A4 (Kd = 7.4 μM). Dietary α-naphthoflavone can contribute to carcinogenesis in the presence of synthetic estrogens.More related product prices
DEXTROMETHORPHAN Fluconazole Naringenin C.I. 75710 RHAPONTIN PONCIRIN 3,5-DIHYDROXY-4'-METHOXYSTILBENE 3-O-BETA-D-GLUCOSIDE α-NaphthoflavoneRelated product price
- DEXTROMETHORPHAN
$21-1220 - Fluconazole
$5-1504.5 - Naringenin
$5-6000
Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Hubei Jusheng Technology Co.,Ltd.
Xi'an Kono chem co., Ltd.,