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α-Naphthoflavone

α-Naphthoflavone
α-Naphthoflavone structure
CAS No.
604-59-1
Chemical Name:
α-Naphthoflavone
Synonyms
BENZOFLAVONE;benzo(h)flavone;-Naphthoflavone;à-naphthoflavone;7,8-BENZOFLAVONE;A-NAPHTHOFLAVONE;1-Naphthoflavone;α-Naphthylflavone;a-Naphthylflavone;NAPHTHOFLAVONE, A-
CBNumber:
CB0184955
Molecular Formula:
C19H12O2
Formula Weight:
272.3
MOL File:
604-59-1.mol

α-Naphthoflavone Properties

Melting point:
153-157 °C(lit.)
Boiling point:
375.35°C (rough estimate)
Density 
1.1382 (rough estimate)
refractive index 
1.5510 (estimate)
storage temp. 
2-8°C
form 
Crystalline Powder or Crystals
color 
yellow
BRN 
210862
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
604-59-1(CAS DataBase Reference)

SAFETY

Hazard Codes  Xi,Xn,C,F
Risk Statements  68-34-11
Safety Statements  24/25-36/37-45-36/37/39-26-16
WGK Germany  3
RTECS  QL6250000
8
Hazard Note  Irritant
TSCA  Yes
HS Code  29143990

α-Naphthoflavone price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N5757 α-Naphthoflavone ≥98% 604-59-1 1g $30.9 2018-11-13 Buy
Sigma-Aldrich N5757 α-Naphthoflavone ≥98% 604-59-1 5g $65.5 2018-11-13 Buy
TCI Chemical B0056 alpha-Naphthoflavone >98.0%(HPLC) 604-59-1 1g $16 2018-11-22 Buy
TCI Chemical B0056 alpha-Naphthoflavone >98.0%(HPLC) 604-59-1 5g $50 2018-11-22 Buy
Alfa Aesar A18542 alpha-Naphthoflavone, 97% 604-59-1 5g $50.1 2018-11-13 Buy

α-Naphthoflavone Chemical Properties,Uses,Production

Chemical Properties

yellow powder

Definition

ChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the h side of flavone. A synthetic compound, it is an inhibitor of aromatase (EC 1.14.14.14).

Uses

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. α-Naphthoflavone is a flavone that modulates xenobiotic metabolism at several points. It antagonizes AhR, blocking the expression of phase I and II genes at nanomolar concentrations, although it can agonize AhR at higher concentrations (10 μM). α-Naphthoflavone inhibits CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50s = 500, 60, 6, and 5 nM, respectively), whereas it activates CYP3A4 (Kd = 7.4 μM). Dietary α-naphthoflavone can contribute to carcinogenesis in the presence of synthetic estrogens.[Cayman Chemical]

Purification Methods

Recrystallise the flavone from EtOH or aqueous EtOH. [IR: Cramer & Windel Chem Ber 89 354 1956, UV Pillon & Massicot Bull Soc Chim Fr 26 1954, Smith J Chem Soc 542

α-Naphthoflavone Preparation Products And Raw materials

Raw materials

Preparation Products


α-Naphthoflavone Suppliers

Global( 140)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19953 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2238 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20229 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3624 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76

View Lastest Price from α-Naphthoflavone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-26 α-Naphthoflavone
604-59-1
US $120.00 / KG 1KG 99% 1000kg career henan chemical co

α-Naphthoflavone Spectrum


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