| | 50264-69-2 Basic information More.. |
| Product Name: | Lonidamine | | Synonyms: | af1890;1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid;1H-Indazole-3-carboxylicacid, 1-[(2,4-dichlorophenyl)Methyl]-;1-(2,4-dichlorbenzyl)-indazole-3-carboxylicacid;1-(2,4-dichlorobenzyl)-1h-indazole-3-carboxylicaci;Lonidamine, >=99%;1-(3,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid;DICLONDAZOLIC ACID | | CAS: | 50264-69-2 | | MF: | C15H10Cl2N2O2 | | MW: | 321.16 | | EINECS: | 256-510-0 | | Mol File: | 50264-69-2.mol |  |
Use
Lonidamine is a derivative of indazole-3-carboxylic acid. It is a kind of orally administrated small molecule, which can inhibit the glycolysis process through inactivating the hexokinase (the first step in glycolysis). It has been shown that cancer cell primarily generates energy through glycolysis process. Therefore, Lonidamine has been used for the treatment of several kinds of cancers. One special property of Lonidamine is that it seems to enhance aerobic glycolysis in normal cells, but inhibit glycolysis only in cancer cells. In addition, there are also evidences that Lonidamine may increase the occurrence of apoptosis. It has also been shown that Lonidamine is effective in the treatment of benigh prostatic hyperplasia (BPH).
- Lonidamine
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- US $9.10 / KG
- 2023-03-06
- CAS:50264-69-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 ton
- Lonidamine
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- US $20.00 / kg
- 2022-08-19
- CAS:50264-69-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000 Ton
- Lonidamine
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- US $9.90-7.70 / g
- 2022-02-23
- CAS:50264-69-2
- Min. Order: 10g
- Purity: 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets，Customiz
- Supply Ability: 1000kgs
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50264-69-2
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