Expectorant grugs, also known as mucokinetic drugs, refer to the medicines that can thin the sputum, reduce its viscosity and accelerate the respiratory mucosal cilia movement to improve the sputum transport function. Expectorant grugs, which can not only help to eliminate sputum and maintain airway patency, but also indirectly relieve the cough and asthma and is conducive to control infection, is an important symptomatic treatment.

Expectorant drugs are divided into:
① nausea and expectorant drugs, which can stimulate the gastric mucosa to cause mild nausea, and make bronchial glandular secretion increase through the vaginal reflex of stomach, resulting the sputum dilution easily coughed up, such as ammonium chloride , Campanulaceae, Polygalaceae, etc .;
② stimulant expectorant, which works by adding volatile substances in hot water and inhaling its vapor to stimulate the respiratory mucosa to cause mucosal congestion and moisten the respiratory tract, resulting that the sputum is easy to cough up, such as eucalyptus oil, Guaiacol;
③ sticky sputum dissolve drugs, which can change the viscous components of sputum and decrease the sputum consistency, such as acetylcysteine and so on.

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Structure Chemical Name CAS MF
Ammonium chloride Ammonium chloride 12125-02-9 ClH4N
Mesna Mesna 19767-45-4 C2H5NaO3S2
p-Cymene p-Cymene 99-87-6 C10H14
Ammonium carbonate Ammonium carbonate 506-87-6 CH8N2O3
Ambroxol hydrochloride Ambroxol hydrochloride 23828-92-4 C13H19Br2ClN2O
Ammonium iodide Ammonium iodide 12027-06-4 H4IN
Guaifenesin Guaifenesin 93-14-1 C10H14O4
Guaiacol carbonate Guaiacol carbonate 553-17-3 C15H14O5
Bromhexine hydrochloride Bromhexine hydrochloride 611-75-6 C14H21Br2ClN2
Bromhexime HCL Bromhexime HCL
Sulfogaiacol Sulfogaiacol 1321-14-8 C7H7KO5S
Ambroxol Ambroxol 18683-91-5 C13H18Br2N2O
Potassium guaiacolsulfonate hemihydrate Potassium guaiacolsulfonate hemihydrate 78247-49-1 C14H16K2O11S2
o-Cresolsulfonic acid o-Cresolsulfonic acid 7134-04-5 C7H8O4S
(-)-MYRTENOL, 97 (-)-MYRTENOL, 97 515-00-4 C10H16O
2-hydroxy-4-methylbenzenesulphonic acid 2-hydroxy-4-methylbenzenesulphonic acid 22356-80-5 C7H8O4S
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