- GTS-21
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- $0.00 / 1KG
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2024-03-16
- CAS:156223-05-1
- Min. Order: 100g
- Purity: 98%+
- Supply Ability: 100kg
- GTS-21
-
- $110.00/ kilogram
-
2023-12-29
- CAS:156223-05-1
- Min. Order: 1kilogram
- Purity: 99%
- Supply Ability: 10 tons/per week
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| | 3-(2,4-dimethoxybenzylidene)anabaseine Basic information |
| Product Name: | 3-(2,4-dimethoxybenzylidene)anabaseine | | Synonyms: | 3-(2,4-dimethoxybenzylidene)anabaseine;3-[(3E)-3-[(2,4-dimethoxyphenyl)methylidene]-5,6-dihydro-4H-pyridin-2-yl]pyridine dihydrochloride;3-(2,4-Dimethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl;3-(2,4)-DiMethoxybenzylidineanabaseine;GTS-21 (DMXB-A);3-(2,4-DiMethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl Dihydrochloride;(3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine dihydrochloride;DMBX-anabaseine | | CAS: | 156223-05-1 | | MF: | C19H22Cl2N2O2 | | MW: | 0 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 156223-05-1.mol |  |
| | 3-(2,4-dimethoxybenzylidene)anabaseine Chemical Properties |
| Melting point | 216-217℃ (decomposition) | | storage temp. | 2-8°C | | solubility | H2O: >5mg/mL | | form | powder | | color | faint yellow to dark yellow | | InChIKey | RPYWXZCFYPVCNQ-RVDMUPIBSA-N |
| WGK Germany | 3 | | RTECS | DW1764860 |
| | 3-(2,4-dimethoxybenzylidene)anabaseine Usage And Synthesis |
| Uses | GTS-21 has been used:
- as an α7 nicotinic acetylcholine receptors (nAChR) partial agonist to elucidate its anti-inflammatory effects in mouse macrophages
- to test its protective effect on the renal injury induced by lipopolysaccharide (LPS)
- to test its effect on microvascular inflammation?in endotoxemia induced by LPS
| | Biochem/physiol Actions | GTS-2, a derivative of anisine is an immunomodulatory drug. It is used for treating pancreatitis and septicemia. GTS-2 inhibits the pro-inflammatory cytokines especially the interleukin-6 (IL6) and tumor necrosis factor (TNF) in sepsis and endotoxemia. |
| | 3-(2,4-dimethoxybenzylidene)anabaseine Preparation Products And Raw materials |
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