| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Thioquinapiperifil
CAS:220060-39-9
Purity:> 95% Remarks:Thioquinapiperifil is a phosphodiesterase-5 (PDE-5) inhibitor used as a dietary supplement.
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| Company Name: |
ChemStrong Scientific Co.,Ltd
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| Tel: |
0755-66853366 13670046396 |
| Email: |
sales@chem-strong.com |
| Products Intro: |
Product Name:Sildenafil Impurity 35
CAS:220060-39-9
Purity:95% HPLC Package:10mg;25mg;50mg
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| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Thioquinapiperifil
CAS:220060-39-9
Purity:>95%
|
| Company Name: |
Wuhan Greenkj Pharmaceutical Technology Co., Ltd.
|
| Tel: |
15608630565 |
| Email: |
greenkjpharm@163.com |
| Products Intro: |
Product Name:3-ethyl-8-[[2-[4-(hydroxymethyl)piperidin-1-yl]phenyl]methylamino]-1H-imidazo[4,5-g]quinazoline-2-thione
CAS:220060-39-9
Purity:98
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| | KF31327 Basic information |
| Product Name: | KF31327 | | Synonyms: | KF31327;3-ethyl-8-[[2-[4-(hydroxymethyl)piperidin-1-yl]phenyl]methylamino]-1H-imidazo[4,5-g]quinazoline-2-thione;Thioquinapiperifil;2H-Imidazo[4,5-g]quinazoline-2-thione, 3-ethyl-1,3-dihydro-8-[[[2-[4-(hydroxymethyl)-1-piperidinyl]phenyl]methyl]amino]-;KF-31327 free base;Thioquinapiperfil | | CAS: | 220060-39-9 | | MF: | C24H28N6OS | | MW: | 448.58 | | EINECS: | | | Product Categories: | | | Mol File: | 220060-39-9.mol |  |
| | KF31327 Chemical Properties |
| | KF31327 Usage And Synthesis |
| Biological Activity | Thioquinapiperifil (KF31327 free base) is a potent, selective, and noncompetitive inhibitor of phosphodiesterase (PDE-5) (IC50 of 0.074 nM) for sexual maturation studies. | | in vitro | Thioquinapiperifil can be found in dietary supplements. Thioquinapiperifil (KF31327 free base) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil (KF31327 free base) are required to inhibit platelet aggregation. | | target | | PDE5 0.074 nM (IC 50 ) | PDE1 380 nM (IC 50 ) | PDE2 670 nM (IC 50 ) | PDE3 38 nM ( IC 50 ) | PDE4 800 nM (IC 50 ) | |
| | KF31327 Preparation Products And Raw materials |
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