舒缓激肽片段1-7
中文名称 | 舒缓激肽片段1-7 |
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中文同义词 | 舒缓激肽片段1-7;BRADYKININ (1-7)|舒缓激肽片段1-7;1-7-血管舒缓激肽;血管舒缓激肽(BK) 片段 (1-7);缓激肽1-7;缓激肽BRADYKININ(1-7) |
英文名称 | H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT |
英文同义词 | H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT;H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACOH;ARG-PRO-PRO-GLY-PHE-SER-PRO;ARG-PRO-PRO-GLY-PHE-SER-PRO ACETATE;BRADYKININ FRAGMENT 1-7;BRADYKININ (1-7);BRADYKININ 1-7 ACETATE;RPPGFSP |
CAS号 | 23815-87-4 |
分子式 | C35H52N10O9 |
分子量 | 756.85 |
EINECS号 | |
相关类别 | 细胞生物学;细胞信号和神经生物学;Peptide;Bradykinins;Peptides and Proteins;Peptides for Cell Biology |
Mol文件 | 23815-87-4.mol |
结构式 |
舒缓激肽片段1-7 性质
储存条件 | −20°C |
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溶解度 | 溶于二甲基亚砜 |
形态 | 粉末 |
颜色 | 白色至米白色 |
水溶解性 | Soluble in water (1 mg/ml). |
The Bradykinin peptide system is a tissue-based system with potent cardiovascular and renal effects. To investigate the regulation of this system, a highly sensitive amino terminal-directed radioimmunoassay that, with high performance liquid chromatography, enables the measurement of Bradykinin-(1-7), Bradykinin-(1-8), and Bradykinin-(1-9), is developed. Together with a carboxy terminal-directed radioimmunoassay, Bradykinin peptides in rat kidney and blood are characterized. The predominant Bradykinin peptides in kidney are Bradykinin-(1-9) (~100 fmol/g wet weight of tissue) and Bradykinin-(1-7) (~70 fmol/g), with low levels of Bradykinin-(1-8) (~8 fmol/g) and Bradykinin-(4-9) (~12 fmol/g) detectable; Bradykinin-(2-9) and Bradykinin-(3-9) are below the limits of detection. In blood, the levels of Bradykinin-(1-9) are very low (~2 fmol/ml), and other Bradykinin peptides are below the limits ofdetection. Administration of the angiotensin converting enzyme (ACE) inhibitor Perindopril is associated with an approximate twofold increase in renal levels of Bradykinin-(1-8) and Bradykinin-(1-9) and a decrease in the Bradykinin-(1-7)/Bradykinin-(1-9) ratio. The amino terminal-directed radioimmunoassay is also applied to heart, aorta, brown adipose tissue, adrenal, lung, and brain. For these tissues, Bradykinin-(1-7) and Bradykinin-(1-9) are of similar abundance (16-340 fmol/g), with lower levels of Bradykinin-(1-8).
安全信息
WGK Germany | 3 |
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提供商 | 语言 |
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英文
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更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-P1484 | 舒缓激肽片段1-7 Bradykinin (1-7) | 23815-87-4 | 5mg | 400元 |
2024/08/19 | HY-P1484 | 舒缓激肽片段1-7 Bradykinin (1-7) | 23815-87-4 | 10mg | 640元 |