| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:PD 176252;(S)-N-[[1-(5-Methoxy-2-pyridinyl)cyclohexyl]Methyl]-α-Methyl-α-[[[-(4-nitrophenyl)aMino]carbonyl]aMino-1H-indole-3-propanaMide
CAS:204067-01-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
|
| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:PD 176252
CAS:204067-01-6
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | (S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE Basic information |
| | (S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE Chemical Properties |
| Boiling point | 838.8±65.0 °C(Predicted) | | density | 1.297±0.06 g/cm3(Predicted) | | storage temp. | Store at +4°C | | solubility | Soluble to 100 mM in DMSO | | form | Powder | | pka | 11.60±0.46(Predicted) |
| | (S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE Usage And Synthesis |
| Biological Activity | Non-peptide gastrin-releasing peptide receptor (GRP-R, BB 2 ) and neuromedin B receptor (NMB-R, BB 1 ) antagonist (K i values are 0.17 and 1.0 nM for BB 1 and BB 2 respectively). Inhibits proliferation of rat C6 glioma cells (IC 50 = 2 μ M) and inhibits NCI-H1299 xenograft proliferation in nude mice (IC 50 = 5 μ M). | | storage | Store at +4°C |
| | (S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE Preparation Products And Raw materials |
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