1-(4-Amino-3-methoxyphenyl)-4-methylpiperazine

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1-(4-Amino-3-methoxyphenyl)-4-methylpiperazine Basic information
Product Name:1-(4-Amino-3-methoxyphenyl)-4-methylpiperazine
Synonyms:2-Methoxy-4-(4-methylpiperazin-1-yl);2-Methoxy-4-(4-methyl-1-piperazinyl)benzenamine;2-Methoxy-4-(4-methylpiperazin-1-yl)benzenamine;BenzenaMine, 2-Methoxy-4-(4-Methyl-1-piperazinyl)-;2-Methoxy-4-(4-methyl-1-piperazinyl)aniline;2-Methoxy-4-(4-methyl-piperazin-1-yl)-phenylamine;2-Methoxy-4-(4-methylpiperazin-1-yl)aniline;Morphinan-3,14-diol,4,5-epoxy-6-(3,6,9,12,15,18,21-heptaoxadocos-1-yloxy)-17-(2-propen-1-yl)-,(5α,6α)-,ethanedioate(1:4)(salt)
CAS:122833-04-9
MF:C12H19N3O
MW:221.3
EINECS:1533716-785-6
Product Categories:
Mol File:122833-04-9.mol
1-(4-Amino-3-methoxyphenyl)-4-methylpiperazine Structure
1-(4-Amino-3-methoxyphenyl)-4-methylpiperazine Chemical Properties
Melting point 73-74°
Boiling point 392℃
density 1.111
Fp 191℃
storage temp. 2-8°C(protect from light)
pka7.78±0.42(Predicted)
AppearanceBrown to black Solid
Safety Information
HS Code 2933599590
MSDS Information
1-(4-Amino-3-methoxyphenyl)-4-methylpiperazine Usage And Synthesis
Uses1-(4-Amino-3-methoxyphenyl)-4-methylpiperazine is a useful synthetic intermediate. It is used to 4,5-dihydro-1H-pyrazolo[4,3-h]quinazolines as orally and selective Polo-like kinase 1 inhibitors. It is also used to synthesize IRAK-4 inhibitors.
1-(4-Amino-3-methoxyphenyl)-4-methylpiperazine Preparation Products And Raw materials
Preparation Products4-(3-aminophenoxy)-5-chloro-N-(2-methoxy-4-(4-methylpiperazin-1- yl)phenyl)pyrimidin-2-amine
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