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Chlorotrimethylsilane

Chlorotrimethylsilane Suppliers list
Company Name: Hangzhou Bayee Chemical Co., Ltd.
Tel: 0086-571-86990109; 0086-18605816692
Email: rachelhoo@bayeechem.com
Products Intro: Product Name:Trimethylchlorosilane
CAS:75-77-4
Purity:99% Min Package:170kg/iron drum or by customer's requirement
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Chlorotrimethylsilane
CAS:75-77-4
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:75-77-4
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Shanghai Time Chemicals CO., Ltd.
Tel: +86-021-57951555
Email: jack.li@time-chemicals.com
Products Intro: Product Name:Chlorotrimethylsilane
CAS:75-77-4
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Email: sales@mainchem.com
Products Intro: Product Name:Chlorotrimethylsilane
CAS:75-77-4

Lastest Price from Chlorotrimethylsilane manufacturers

  • Chlorotrimethylsilane
  • US $2.00 / KG
  • 2019-05-13
  • CAS:75-77-4
  • Min. Order: 10KG
  • Purity: 99%
  • Supply Ability: 20kg
Chlorotrimethylsilane Chemical Properties
Melting point −40 °C(lit.)
Boiling point 57 °C(lit.)
density 0.857 g/mL at 25 °C
vapor density 3.7 (vs air)
vapor pressure 100 mm Hg ( 25 °C)
refractive index n20/D 1.500
Fp 104 °F
storage temp. Store at RT.
solubility Miscible with ether, benzene, diethylether and perchloroethylene.
form Liquid
Specific Gravity0.8536 (27℃)
color Clear colorless
explosive limit1.5-46%(V)
Water Solubility REACTS
Sensitive Moisture Sensitive
BRN 1209232
Stability:Stable. Highly flammable - note low flash point. Reacts violently with water. Incompatible with water, moisture, strong oxidizing agents, strong acids, strong bases, aldehydes, alcohols, amines, esters, ketones.
InChIKeyIJOOHPMOJXWVHK-UHFFFAOYSA-N
CAS DataBase Reference75-77-4(CAS DataBase Reference)
NIST Chemistry ReferenceSilane, chlorotrimethyl-(75-77-4)
EPA Substance Registry SystemSilane, chlorotrimethyl-(75-77-4)
Safety Information
Hazard Codes T,F,C,Xn
Risk Statements 20/21-36/38-34-21-14-11-37-35-19-40-10-67-20/21/22-52
Safety Statements 26-36/37/39-45-16-36/37-7/9
RIDADR UN 2924 3/PG 2
WGK Germany 2
RTECS VV2710000
10-21
Autoignition Temperature752 °F
Hazard Note Highly Flammable/Corrosive/Moisture Sensitive
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29310095
Hazardous Substances Data75-77-4(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 4868 mg/kg LD50 dermal Rabbit 1530 mg/kg
MSDS Information
ProviderLanguage
Chlorotrimethylsilane English
ACROS English
SigmaAldrich English
ALFA English
Chlorotrimethylsilane Usage And Synthesis
Chemical PropertiesA clear, colorless, caustic and highly flammable liquid with a pungent odour. Readily hydrolyzed with liberation of hydrogen chloride; soluble in benzene, ether and perchloroethylene.
Chemical PropertiesTrimethylchlorosilane is a colorless, fuming liquid. Irritating odor.
UsesChlorotrimethylsilane is a typical Silane Blocking Agent, which can protect or deprotect functional groups selectively. It is widely used in the syntheses of drugs. It have been used in the preparation of volatile derivatives of a wide range of compounds for GC analysis, and used for silylation and as a protection group in the process of various organic synthesis.
DefinitionChEBI: A silyl chloride consisting of a central silicon atom covalently bound to one chloro and three methyl groups. Chlorotrimethylsilane is a derivatisation agent used in gas chromatography/mass spectrometry applications.
General DescriptionA colorless fuming liquid with a pungent odor. Boiling point 135°F Flash point -18°F. Density 0.854 g / cm3. The vapor and liquid may cause burns. Vapors are heavier than air.
Reactivity ProfileChlorotrimethylsilane reacts vigorously and exothermically with water to produce hydrogen chloride.
Health HazardSimilar to other silanes. Toxicity is rated high for inhalation, ingestion and local irritation. May cause death or permanent injury after a very short exposure to small quantities.
Fire HazardViolent reaction with water. Toxic and irritating hydrogen chloride and phosgene may be formed in fires. Difficult to extinguish, re-ignition may occur. Flashback along vapor trail may occur. Containers may explode in fire. Vapor may explode if ignited in enclosed area. When heated to decomposition or on contact with acids or acid fumes, chloride fumes are emitted. Reacts with surface moisture, releasing hydrogen chloride, which will corrode common metals and form flammable hydrogen gas. Avoid contact with water; Chlorotrimethylsilane readily hydrolyzes, liberating hydrochloric acid. Hazardous polymerization may not occur.
Safety ProfilePoison by ingestion and skin contact. Moderately toxic by inhalation and intraperitoneal routes. A corrosive irritant to skin, eyes, and mucous membranes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. A flammable liquid and very dangerous fire hazard when exposed to heat or flame. Violent reaction with water or hexafluoroisopropylideneamino lithium, A preparative hazard. To fight fire, use foam, alcohol foam, fog. When heated to decomposition it emits toxic fumes of Cl-. An intermediate in the production of silicones. See also CHLOROSILASES.
Potential ExposureTrimethylchlorosilane is used as an intermediate to make silicone products, including lubricants
First aidIf this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 30 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. If victim is conscious, administer water, or milk. Do not induce vomiting. Medical observation is recommended for 24-48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.
ShippingUN1298 Trimethylchlorosilane, Hazard Class: 3; Labels: 3-Flammable liquid, 8-Corrosive material.
Purification MethodsLikely impurities are other chlorinated methylsilanes and tetrachlorosilane (b 57.6o), some of which can form azeotropes. To avoid the latter, very efficient fractional distillation is required. It has been fractionated through a 12 plate glass helices-packed column with only the heart-cut material being used. It has also been fractionated through a 90cm, 19mm diameter Stedman column (p 11). Purify it by redistilling from CaH2 before use. [Sauer et al. J Am Chem Soc 70, 4254 1948, Sauer & Hadsell J Am Chem Soc 70 4258 1948, Langer et al. J Org Chem 23 50 1958, Beilstein 4 IV 4007.] FLAMMABLE and CORROSIVE.
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Chlorosilanes react vigorously with bases and both organic and inorganic acids generating toxic and/or flammable gases. Chlorosilanes react with water, moist air, or steam to produce heat and toxic, corrosive fumes of hydrogen chloride. They may also produce flammable gaseous hydrogen. Attacks metals in the presence of moisture. Vigorous reaction with aluminum powder.
Waste DisposalDo not discharge into drains or sewers. Use a licensed disposal contractor to an approved landfill. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office for guidance on acceptable disposal practices. The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material’s impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.
Chlorotrimethylsilane Preparation Products And Raw materials
Preparation Products(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-phenylacetic acid-->5-FLUORO-2-PICOLINIC ACID-->(Trifluoromethyl)trimethylsilane-->Hexamethyldisilazane-->Thiophene-2-ethylamine-->Rhodanine-3-acetic acid-->Pyridine sulfur trioxide-->6-IODO-PYRIDINE-2-CARBOXYLIC ACID-->Cefoperazone-->1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE-->Trimethylsilylacetylene-->(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid-->4-AMINO-2,6-DIFLUORO-BENZALDEHYDE-->Hexamethyldisiloxane-->2,4-DIMETHOXYPHENETHYLAMINE-->5-BROMO-3-FLUORO-2-PYRIDINONE-->5-BROMO-3-CHLORO-2-PYRIDINONE-->Aniracetam-->TRIS(TRIMETHYLSILYL)SILANE-->Thiazole-4-carboxaldehyde-->6-CYANONICOTINIC ACID-->ROKITAMYCIN-->2-(TRIMETHYLSILYL)PHENYL TRIFLUOROMETHANESULFONATE-->7-Aminocephalosporanic acid-->Bis(trimethylsilyl)acetylene-->2,4-DIMETHYLQUINOLINE-3-CARBOXYLIC ACID-->Azidotrimethylsilane-->4'-Iodoacetophenone-->Ethoxytrimethylsilane-->2-ETHYL-4-METHYLQUINOLINE-3-CARBOXYLIC ACID-->BIS(TRIMETHYLSILYL)PEROXIDE-->ETHYL 2,4-DIMETHYLQUINOLINE-3-CARBOXYLATE-->ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE-->ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE-->Tegafur-->1-(2,4-DIMETHYLQUINOLIN-3-YL)ETHANONE HYDROCHLORIDE-->ETHYL 2-(CHLOROMETHYL)-4-METHYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE-->METHYL 2-(CHLOROMETHYL)-4-METHYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE-->N,O-Bis(trimethylsilyl)acetamide-->Allyltrimethylsilane
Raw materialsAcetyl chloride-->Cuprous chloride-->METHYL CHLORIDE-->Silicon-->Chloromethyl silane-->Tetramethylsilane
Tag:Chlorotrimethylsilane(75-77-4) Related Product Information
Dimethyldimethoxysilane Hexamethyldisilane Trifluoroacetic acid Triethylamine (Trifluoromethyl)trimethylsilane Choline chloride Polyvinyl chloride Potassium chloride Bromotrimethylsilane Chloromethyl silane DIMETHYLTHEXYLSILYL CHLORIDE Sodium chloride Benzyl chloride TRIMETHYLSILANE CHLOROPHENYLSILANE 97 CHLORIDE STANDARD Calcium chloride Iodotrimethylsilane