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p-Anisidine

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Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:4-Methoxyaniline
CAS:104-94-9
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
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Products Intro: Product Name:p-Anisidine
CAS:104-94-9
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
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Products Intro: CAS:104-94-9
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Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
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Products Intro: Product Name:p-Anisidine
CAS:104-94-9
Purity:99.5 Package:1ASSAYS;1USD
Company Name: career henan chemical co
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Products Intro: Product Name:p-Anisidine
CAS:104-94-9
Purity:98%min Package:1kg;1USD

Lastest Price from p-Anisidine manufacturers

  • p-Anisidine
  • 2020-12-01
  • CAS:104-94-9
  • Min. Order: 1KG
  • Purity: 99.99
  • Supply Ability: 10Ton
  • p-Anisidine
  • US $1.00 / KG
  • 2020-01-03
  • CAS: 104-94-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20T
  • p-Anisidine
  • US $1.00 / kg
  • 2019-07-06
  • CAS:104-94-9
  • Min. Order: 1kg
  • Purity: 98%min
  • Supply Ability: 1000kg
p-Anisidine Basic information
Product Name:p-Anisidine
Synonyms:P-AMINOANISOLE;4-[4-(4-Aminophenyl)phenyl]aniline;p,p'-Diaminoterphenyl;1,4-Anisidine;p-Anisidine,95%,pract.;1-Methoxy-4-amino-benzen (p-anisidin);1-Methoxy-4-amino-benzene / p-anisidine;4-Methoxy-1-aminobenzene
CAS:104-94-9
MF:C7H9NO
MW:123.15
EINECS:203-254-2
Product Categories:Thiophenes;amine;Intermediates of Dyes and Pigments;Intermediates;Anilines (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials
Mol File:104-94-9.mol
p-Anisidine Structure
p-Anisidine Chemical Properties
Melting point 56-59 °C(lit.)
Boiling point 240-243 °C(lit.)
density 1.06
vapor density 4.28
vapor pressure 0.02 hPa (20 °C)
refractive index 1.5559
Fp 122 °C
storage temp. 2-8°C
solubility 21g/l
pka5.34(at 25℃)
form crystalline
Specific Gravity1.07
color dark gray to brown
PH7.7 (1g/l, H2O, 20℃)
Water Solubility 21 g/L (20 ºC)
Merck 14,667
BRN 471556
Henry's Law Constant(x 10-8 atm?m3/mol): 6.62 at 25 °C (thermodynamic method-GC/UV spectrophotometry, Altschuh et al., 1999)
Exposure limitsNIOSH REL: TWA 0.5 mg/m3, IDLH 50 mg/m3; OSHA PEL: TWA 0.5 mg/m3; ACGIH TLV: TWA 0.1 ppm (adopted).
CAS DataBase Reference104-94-9(CAS DataBase Reference)
IARC3 (Vol. 27, Sup 7) 1987
NIST Chemistry ReferenceBenzenamine, 4-methoxy-(104-94-9)
EPA Substance Registry Systemp-Anisidine (104-94-9)
Safety Information
Hazard Codes T+,N,Xi
Risk Statements 45-26/27/28-33-50
Safety Statements 53-28-36/37-45-61-28A
RIDADR UN 2811 6.1/PG 3
WGK Germany 2
RTECS BZ5450000
8
Autoignition Temperature959 °F
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29222200
Hazardous Substances Data104-94-9(Hazardous Substances Data)
ToxicityAcute oral LD50 for rats 1,400 mg/kg, mice 810 mg/kg, rabbits 2,900 mg/kg (quoted, RTECS, 1985).
MSDS Information
ProviderLanguage
4-Methoxybenzeneamine English
SigmaAldrich English
ACROS English
ALFA English
p-Anisidine Usage And Synthesis
Chemical PropertiesAnisidine exists as ortho-, meta-, and paraisomers. They have characteristic amine (fishy) odors.
Chemical Propertiesgrey to brown crystalline powder, granules
Physical propertiesYellow to light brown powder, leaflets, solid or crystals with a characteristic amine or ammonialike odor
Usesp-Anisidine is used mostly for producing dyes, and some smaller quantities are employed in making pharmaceuticals and liquid crystals.
UsesIn the preparation of azo dyes; corrosion inhibitor; chemical intermediate
Usesp-Anisidine is used as a reagent to indicate the secondary stage of the oxidation, it is one of the three possible isomers of the Anisidine or methoxyaniline. The other two isomers are o-Anisidine (2-methoxyaniline) and m-Anisidine (3-methoxyaniline).
The p-anisidine is widely used as an intermediate in the production of numerous azo and triphenylmethane dyes, and pigments. It is also used in the production of pharmaceuticals including the guaiacol expectorant, as an antioxidant for polymercaptan resins, and as a corrosion inhibitor for steel. Apart from the beneficial use of p-anisidine, it is toxic for human beings. The acute exposure may cause skin irritation, whereas the chronic exposure may cause headaches, vertigo, and blood complications like sulfhemoglobin, and methemoglobin. The oral exposure to anisidine hydrochloride resulted in cancer of the urinary bladder in male and female rats.
https://www.longdom.org/open-access/physicochemical-and-spectroscopic-characterization-of-biofield-energytreated-panisidine-paco-1000102.pdf
Synthesis Reference(s)Journal of the American Chemical Society, 99, p. 98, 1977 DOI: 10.1021/ja00443a018
The Journal of Organic Chemistry, 49, p. 1434, 1984 DOI: 10.1021/jo00182a023
Tetrahedron Letters, 21, p. 2603, 1980 DOI: 10.1016/S0040-4039(00)92816-8
General DescriptionBrown crystals or dark brown solid. Characteristic amine odor.
Air & Water ReactionsInsoluble in water.
Reactivity Profilep-Anisidine may be sensitive to heat, light and moisture. Reacts with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents. Incompatible with alkaline materials. Incompatible with aldehydes, ketones and nitrates.
HazardStrong irritant. Toxic when absorbed through the skin. Questionable carcinogen.
Fire Hazardp-Anisidine is flammable.
Safety ProfileModerately toxic by several routes. A mild sensitizer. May cause a contact dermatitis. Mutation data reported. Questionable carcinogen. See also ANILINE. When heated to decomposition it emits toxic fumes of Nox
Potential ExposureAnisidines are used in the manufacture of azo dyes; pharmaceuticals; textile-processing chemicals Incompatibilities: Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Attacks some coatings and some forms of plastic and rubber.
CarcinogenicityAvailable data were inadequate to evaluate the carcinogenicity of p-anisidine.
Environmental fateChemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987).
ShippingUN2431 Anisidines, Hazard Class: 6.1; Labels: 6.1-Poisonous materials
Purification MethodsCrystallise p-anisidine from H2O or aqueous EtOH. Dry it in a vacuum oven at 35o for 6hours and store it in a dry box. [More et al. J Am Chem Soc 108 2257 1986.] Purify it also by vacuum sublimation [Guarr et al. J Am Chem Soc 107 5104 1985]. [Beilstein 13 IV 1015.]
Waste DisposalDissolve in combustible solvent (alcohols, benzene, etc.) and spray solution into furnace equipped with afterburner and scrubber, or burn spill residue on sand and soda ash absorbent in a furnace.
Tag:p-Anisidine(104-94-9) Related Product Information
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