Cngrcggklaklakklaklak-NH2 (disulfide bridge: 1-5)

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Cngrcggklaklakklaklak-NH2 (disulfide bridge: 1-5) Suppliers list
Company Name: GL Biochem (Shanghai) Ltd  
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Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
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Company Name: Chemsky (shanghai) International Co.,Ltd  
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Company Name: Creative Peptides   
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Company Name: Nanjing Peptide Biotech Ltd.  
Tel: 025-58361106-805 15951641583
Email: zhao.xu@njpeptide.com
Cngrcggklaklakklaklak-NH2 (disulfide bridge: 1-5) Basic information
Product Name:Cngrcggklaklakklaklak-NH2 (disulfide bridge: 1-5)
Synonyms:CNGRCGGklaklakklaklak-NH2 (Disulfide bond), CNGRC-GG-(klaklak)2-NH2 (Disulfide bond);NGR PEPTIDE 1;TUMOR TARGETED PRO-APOPTOTIC PEPTIDE;CNGRC-GG-(KLAKLAK)2-NH2 (DISULFIDE BOND);CNGRCGGKLAKLAKKLAKLAK-NH2;CNGRCGGKLAKLAKKLAKLAK-NH2 (DISULFIDE BOND);H-CYS-ASN-GLY-ARG-CYS-GLY-GLY-D-LYS-D-LEU-D-ALA-D-LYS-D-LEU-D-ALA-D-LYS-D-LYS-D-LEU-D-ALA-D-LYS-D-LEU-D-ALA-D-LYS-NH2;H-CYS-ASN-GLY-ARG-CYS-GLY-GLY-D-LYS-D-LEU-D-ALA-D-LYS-D-LEU-D-ALA-D-LYS-D-LYS-D-LEU-D-ALA-D-LYS-D-LEU-D-ALA-D-LYS-NH2 (DISULFIDE BRIDGE: 1-5)
CAS:1926163-30-5
MF:C94H174N32O22S2
MW:2168.72
EINECS:
Product Categories:peptide
Mol File:Mol File
Cngrcggklaklakklaklak-NH2 (disulfide bridge: 1-5) Structure
Cngrcggklaklakklaklak-NH2 (disulfide bridge: 1-5) Chemical Properties
density 1.42±0.1 g/cm3(Predicted)
Safety Information
MSDS Information
Cngrcggklaklakklaklak-NH2 (disulfide bridge: 1-5) Usage And Synthesis
UsesTumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis, showing anticancer activity in mice[1].
in vivo

Tumor targeted pro-apoptotic peptide inhibits both primary tumor growth and metastasis in mice[1].

Animal Model:Tumor targeted pro-apoptotic peptide (250 μg/mice; tail vein injection; 250 μg a week for 17 weeks) inhibits both primary tumor growth and metastasis in mice[1].
Dosage:250 μg/mice
Administration:Tail vein injection; 250 μg a week for 17 weeks
Result:Exhibited antitumor activity in vivo.
References[1] Ellerby HM, et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med. 1999 Sep;5(9):1032-8. DOI:10.1038/12469
Cngrcggklaklakklaklak-NH2 (disulfide bridge: 1-5) Preparation Products And Raw materials
Tag:Cngrcggklaklakklaklak-NH2 (disulfide bridge: 1-5)(1926163-30-5) Related Product Information
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