2,4,5-TRIFLUOROBENZYL CHLORIDE manufacturers
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| | 2,4,5-TRIFLUOROBENZYL CHLORIDE Basic information |
| Product Name: | 2,4,5-TRIFLUOROBENZYL CHLORIDE | | Synonyms: | 2,4,5-TRIFLUOROBENZYL CHLORIDE;2,4,5-TRIFLUOROBENZYL CHORIDE;Benzene, 1-(chloromethyl)-2,4,5-trifluoro- (9CI);1-(Chloromethyl)-2,4,5-trifluorobenzene, alpha-Chloro-2,4,5-trifluorotoluene;Sitagliptin Impurity 70;Benzene, 1-(chloromethyl)-2,4,5-trifluoro-;alpha-Chloro-2,4,5-trifluorotoluene | | CAS: | 243139-71-1 | | MF: | C7H4ClF3 | | MW: | 180.55 | | EINECS: | | | Product Categories: | Fluorine series;HALOMETYL;Miscellaneous | | Mol File: | 243139-71-1.mol |  |
| | 2,4,5-TRIFLUOROBENZYL CHLORIDE Chemical Properties |
| Boiling point | 175℃ | | density | 1,689 g/cm3 | | refractive index | 1.5050 | | Fp | 65°C | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | clear liquid | | color | Colorless to Almost colorless | | InChI | InChI=1S/C7H4ClF3/c8-3-4-1-6(10)7(11)2-5(4)9/h1-2H,3H2 | | InChIKey | JMXPOOVDUVHJRO-UHFFFAOYSA-N | | SMILES | C1(CCl)=CC(F)=C(F)C=C1F | | CAS DataBase Reference | 243139-71-1(CAS DataBase Reference) |
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ALFA
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| | 2,4,5-TRIFLUOROBENZYL CHLORIDE Usage And Synthesis |
| Chemical Properties | Colorless to Almost colorless clear liquid. | | Uses | 2,4,5-Trifluorobenzyl chloride is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor that decreases in
glucagon to improve control of blood sugar used for the treatment of
type 1 diabetes, 79% of the dose excreted in the urine. | | Uses | 2,4,5-Trifluorobenzyl chloride is a useful research chemical. | | Synthesis | On the four-neck flask, install a stirrer, a thermometer, a chlorine gas pipe and a reflux condenser. The reflux condenser is connected to the HCl absorption system, and a light source is installed near the flask.Add 146.0g 2,4,5-trifluorotoluene and 3.0g azobisisobutyronitrile into the reaction flask, stir and heat, and when the temperature rises to 110°C, add dry chlorine gas, and Using GC tracking, after about 3h of chlorine gas, stop the halogenating agent chlorine gas, cool the reactant, wash it with water to neutrality, dry and distill under reduced pressure to obtain 2,4,5-trifluorobenzyl chloride. |
| | 2,4,5-TRIFLUOROBENZYL CHLORIDE Preparation Products And Raw materials |
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