N-Methyl-1H-imidazole-4-ethanamine dihydrochloride

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N-Methyl-1H-imidazole-4-ethanamine dihydrochloride Basic information
Product Name:N-Methyl-1H-imidazole-4-ethanamine dihydrochloride
Synonyms:4-(2-methylaminoethyl)imidazole;4-(2-(methylamino)ethyl)-imidazol;methylhistamine;n(supalpha)-methylhistamine;n’-methylhistamine;n-methyl-1h-imidazole-4-ethanamin;IMIDAZOLE,4-(2-(METHYLAMINO)ETHYL)-;NA-METHYLHISTAMINE DIHYDROCHLORIDE
CAS:673-50-7
MF:C6H11N3
MW:125.17
EINECS:
Product Categories:Histamine receptor
Mol File:673-50-7.mol
N-Methyl-1H-imidazole-4-ethanamine dihydrochloride Structure
N-Methyl-1H-imidazole-4-ethanamine dihydrochloride Chemical Properties
Melting point 188-189 °C
Boiling point 309.1±17.0 °C(Predicted)
density 1.050±0.06 g/cm3(Predicted)
storage temp. Store at RT
pka14.58±0.10(Predicted)
Safety Information
MSDS Information
N-Methyl-1H-imidazole-4-ethanamine dihydrochloride Usage And Synthesis
Uses2-(1H-Imidazol-5-yl)-N-methylethanamine is a metabolite of histamine.
DefinitionChEBI: N-alpha-Methylhistamine is an aralkylamine.
Synthesis Reference(s)Tetrahedron, 23, p. 239, 1967 DOI: 10.1016/S0040-4020(01)83305-6
Biological ActivityPotent histamine agonist, particularly at H 3 receptors (potency relative to histamine is 81, 185, and 270% at H 1 , H 2 and H 3 respectively). Also displays agonist properties at H 4 receptors to which it binds with moderate affinity (K i = 23 nM).
N-Methyl-1H-imidazole-4-ethanamine dihydrochloride Preparation Products And Raw materials
Tag:N-Methyl-1H-imidazole-4-ethanamine dihydrochloride(673-50-7) Related Product Information
Alpidem N-Methyl-1H-imidazole-4-ethanamine dihydrochloride (S)-(+)-alpha-Methyl-1H-imidazole-4-ethanamine dihydrobromide H-Phe-His-OMe 2 HCl (R)-(-)-alpha-Methylhistamine dihydrobromide 4,5,6,7-Tetrahydro-1H-imidazol[4,5-c]-pyridine dihydrochloride 2-Methyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine dihydrochloride Na-benzyl-L-histidine methyl esterdihydr ochloride 3-Methylhistamine dihydrochloride Ac-Cys-Glu-His-dicl-D-Phe-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2 4-(2,3-Dichloro-phenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid 4-(2,4-Dichloro-phenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid H-D-His(Trt)-OMe 2HCl Methylhistamine dihydrochloride, N-alpha-[methyl-3H]- Iflab-bb F1824-0006 PTH-histidine 2HCl H2O 2,4-Dichloro-N-((1E)-[(4,6-dimethylpyrimidin-2-yl)amino]{[2-(1H-imidazol-4-yl)ethyl]amino}methylene)benzamide N-(3,4-Dichlorophenyl)-N'-((1E)-[(4,6-dimethylpyrimidin-2-yl)amino]{[2-(1H-imidazol-4-yl)ethyl]amino}methylene)urea