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N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE

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Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:W-13 hydrochloride
CAS:88519-57-7
Package:10 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Dayang Chem (Hangzhou) Co.,Ltd.
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Products Intro: Product Name:N-(4-Aminobutyl)-5-Chloronaphthalene-2-Sulfonamide Hydrochloride
CAS:88519-57-7
Purity:0.95&0.99 Package:0.1KG;1KG;1000KG Remarks:High quality
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
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Products Intro: Product Name:N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
CAS:88519-57-7
Purity:N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLO Package:1g;5g;10g Remarks:98% HPLC
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
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Products Intro: Product Name:N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide hydrochloride
CAS:88519-57-7
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Aladdin Scientific
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Products Intro: Product Name:W-13 hydrochloride
CAS:88519-57-7
Purity:95% Package:$74.9/5mg;$153.9/10mg;$256.9/25mg;$616.9/50mg;Bulk package Remarks:95%

N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE manufacturers
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Basic information
Product Name:N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
Synonyms:N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENE SULPHONAMIDE, HYDROCHLORIDE;OMEGA-13 HYDROCHLORIDE;W-13;W-13 HYDROCHLORIDE;N-(4-Aminohexyl)-5-chloro-2-naphthalenesulfonamide hydrochloride;(+)-5-Hydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one;N-(4-Aminobutyl)-5-chloronaphthalene-2-sulphonamide hydrochloride
CAS:88519-57-7
MF:C14H18Cl2N2O2S
MW:349.28
EINECS:
Product Categories:All Inhibitors;Inhibitors;Protein Kinase Inhibitors and Activators;Calcium signaling;Amines;Aromatics;Sulfur & Selenium Compounds
Mol File:88519-57-7.mol
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Structure
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Chemical Properties
Melting point 241-243°C
storage temp. room temp
solubility H2O: Stock solutions of 5 mM are recommended. These stocks should be stable for up to 6 months when stored at 4°C.soluble
form powder
color white
CAS DataBase Reference88519-57-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 2935.90.9500
MSDS Information
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SigmaAldrich English
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Usage And Synthesis
DescriptionW-13 is a naphthalenesulfonamide derivative that acts as a potent antagonist of calmodulin (IC50 = 22 μM) and is widely used to investigate Ca2+/calmodulin-regulated enzyme activities.
Chemical PropertiesBeige Solid
UsesCalmodulin antagonist that binds to calmodulin and inhibits calcium-ion-calmodulin- regulated activities, including phosphodiesterase activation and myosin light chain kinase127, it is widely used to investigate Ca2+/calmodulin-regulated enzyme activities.
UsesW-13 is a naphthalenesulfonamide derivative that acts as a potent antagonist of calmodulin (IC50 = 22 μM) and is widely used to investigate Ca2+/calmodulin-regulated enzyme activities.
DefinitionChEBI: N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide hydrochloride is a hydrochloride salt prepared from equimolar amounts of N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide and hydrogen chloride. It contains a N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide(1+).
Biological ActivityCalmodulin antagonist (inhibits calmodulin activated PDE activity with an IC 50 of 68 μ M). Inhibits growth of tamoxifen-resistant breast cancer cells.
Biochem/physiol ActionsW-13 has also been shown to inhibit the transcytosis of IgA, recycling of transferrin and overall alter the endocytic pathway in Madin-Darby canine kidney cells.
storageStore at RT
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Preparation Products And Raw materials
Tag:N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE(88519-57-7) Related Product Information
BenzenesulfonaMide, 4-chloro-N-[1-(2-phenylethyl)-2-piperidinylidene]- (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE W-5 HYDROCHLORIDE W123 Exclusive [(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Naphthalene Carbon tetrachloride Propylene oxide N-TERT-BUTYL-ALPHA-PHENYLNITRONE N-(4-AMINOBUTYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE, HYDROCHLORIDE NAPHTHALENE-2-SULFONAMIDE 1-Chloronaphthalene 1,4-Diaminobutane dihydrochloride N-(4-AMINOBUTYL)-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE