(2R,3R)-2-Amino-3-methylpentanoic acid

(2R,3R)-2-Amino-3-methylpentanoic acid Suppliers list

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(2R,3R)-2-Amino-3-methylpentanoic acid manufacturers

Synthesis and Physiological Activity of (2R,3R)-2-Amino-3-methylpentanoic acid
(2R,3R)-2-Amino-3-methylpentanoic acid serves as an important intermediate for the synthesis of antibacterial, antitumor.
Aug 7，2026

(2R,3R)-2-Amino-3-methylpentanoic acid Basic information

Product Name:	(2R,3R)-2-Amino-3-methylpentanoic acid
Synonyms:	(2R,3R)-2-Amino-3-methylvaleric acid;D-Isoleucine≥ 98% (TLC);D(-)-ISOLEUCINE;[-]-2-AMINO-3-METHYLPENTANOIC ACID;H-D-lle-OH;D-isoleucine (99% ee/glc);D-ISOLEUCINE, (2R,3R)-2-AMINO-3-METHYL-PENTANOIC ACID;(2R,3R)-2-AMINO-3-METHYLPENTANOIC ACID
CAS:	319-78-8
MF:	C6H13NO2
MW:	131.17
EINECS:	206-269-2
Product Categories:	Amino Acid Derivatives;Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids;bc0001
Mol File:	319-78-8.mol

(2R,3R)-2-Amino-3-methylpentanoic acid Chemical Properties

Melting point	272-274 °C
alpha	-37 º (c=5, 1 N HCl 24 ºC)
Boiling point	225.8±23.0 °C(Predicted)
density	1.1720 (estimate)
refractive index	-40.5 ° (C=4, 6mol/L HCl)
storage temp.	Sealed in dry,Room Temperature
solubility	Aqueous Acid (Slightly), Water (Slightly)
pka	2.57±0.24(Predicted)
form	Solid
color	White to Off-White
Major Application	cell analysis
InChI	InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m1/s1
InChIKey	AGPKZVBTJJNPAG-RFZPGFLSSA-N
SMILES	C(O)(=O)[C@@H]([C@H](C)CC)N
CAS DataBase Reference	319-78-8(CAS DataBase Reference)
EPA Substance Registry System	D-Isoleucine (319-78-8)

Safety Information

Hazard Codes	Xn
Risk Statements	40
Safety Statements	24/25-36-22
WGK Germany	3
RTECS	NR4700000
HS Code	29224995
Storage Class	11 - Combustible Solids
Toxicity	rat,LD50,intraperitoneal,6822mg/kg (6822mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)LUNGS, THORAX, OR RESPIRATION: DYSPNEA,Archives of Biochemistry and Biophysics. Vol. 64, Pg. 319, 1956.

MSDS Information

Provider	Language
(2R,3R)-2-Amino-3-methylpentanoic acid	English
SigmaAldrich	English
ACROS	English

(2R,3R)-2-Amino-3-methylpentanoic acid Usage And Synthesis

Chemical Properties	white to very slightly yellow powder
Uses	D-Isoleucine is not biosynthesized in the human body and is therefore categorized as an essential amino acid that must be obtained through diet. It is also an important building block that is used in the formation of hemoglobin in humans.
Uses	May contain up to 10% allo-isomer.
Definition	ChEBI: The D-enantiomer of isoleucine.
Biological Activity	D-Isoleucine may be used to help characterize and differentiate various D-amino acid oxidases. D-Isoleucine may be used to differentiate the activities of D- and L-isoleucine in processes such as the induction of pigmentation in B16F0 melanoma cells.

(2R,3R)-2-Amino-3-methylpentanoic acid Preparation Products And Raw materials

Raw materials	Acetic anhydride-->L-Isoleucine
Preparation Products	L-Isoleucine-->Cyclo(Ile-Ala)

Tag:(2R,3R)-2-Amino-3-methylpentanoic acid(319-78-8) Related Product Information

Boc-alpha-Cyclohexyl-D-glycine Boc-D-Cyclopentylglycine D-alpha-Cyclohexylglycine Fmoc-D-Ile-OH Boc-D-isoleucine Methyl L-isoleucinate Fmoc-Ile-OH Fmoc-L-allo-isoleucine Methyl L-isoleucinate hydrochloride N-Cbz-L-Isoleucine Calcium (S)-3-methyl-2-oxovalerate N-Cbz-N-methyl-L-isoleucine Calcium 3-methyl-2-oxovalerate Z-D-Phg-OH Fmoc-Chg-OH Fmoc-D-allo-Ile-OH Fmoc-D-Chg-OH 4-Hydroxyisoleucine