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| | 5,6-DICHLOROBENZIMIDAZOLE-2-THIOL Basic information |
| Product Name: | 5,6-DICHLOROBENZIMIDAZOLE-2-THIOL | | Synonyms: | 5,6-DICHLOROBENZIMIDAZOLE-2-THIOL;5,6-DICHLORO-2-MERCAPTOBENZIMIDAZOLE;5,6-DICHLORO-1H-BENZO[D]IMIDAZOLE-2-THIOL;5,6-DICHLORO-1H-BENZIMIDAZOLE-2-THIOL;5,6-Dichloro-1H-benzo[d]imidazole-2-thiol, 5,6-Dichloro-2-mercaptobenzimidazole;5,6-dichloro-1H-1,3-benzodiazole-2-thiol;5,6-Dichloro-1H-benzo[d]imidazole-2-thiol, 95+%;5,6-dichloro-1,3-dihydrobenzimidazole-2-thione | | CAS: | 19462-98-7 | | MF: | C7H4Cl2N2S | | MW: | 219.09 | | EINECS: | | | Product Categories: | | | Mol File: | 19462-98-7.mol |  |
| | 5,6-DICHLOROBENZIMIDAZOLE-2-THIOL Chemical Properties |
| Melting point | 300 °C | | Boiling point | 329.8±52.0 °C(Predicted) | | density | 1.68±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 8.76±0.30(Predicted) | | Appearance | White to off-white Solid | | Water Solubility | Insoluble in water. | | CAS DataBase Reference | 19462-98-7 |
| Risk Statements | 36/37/38 | | Safety Statements | 26-37 | | HS Code | 2933998090 |
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ALFA
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| | 5,6-DICHLOROBENZIMIDAZOLE-2-THIOL Usage And Synthesis |
| Uses | It is employed in the synthesis of 2,3-dideoxy and 2,3-unsaturated ribofuranonucleosides as potential antiviral agents. | | Synthesis | GENERAL METHOD: 4,5-Dichloro-1,2-phenylenediamine (0.065 mol) was heated to reflux with N-amino winding tannin (0.065 mol) in xylene (50 mL) for 5 hours. After completion of the reaction, it was cooled to room temperature and the precipitate was collected by filtration. The crude product was purified by thermal crystallization using aqueous ethanol (containing activated carbon). The resulting solid was further recrystallized in ethanol to give 2-mercapto-5,6-dichlorobenzimidazole. | | References | [1] Oriental Journal of Chemistry, 2016, vol. 32, # 4, p. 1765 - 1768 |
| | 5,6-DICHLOROBENZIMIDAZOLE-2-THIOL Preparation Products And Raw materials |
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