Octreotide (Dimer, Parallel) manufacturers
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| | Octreotide (Dimer, Parallel) Basic information |
| Product Name: | Octreotide (Dimer, Parallel) | | Synonyms: | Octreotide (Dimer, Parallel);L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, bimol. cyclic (2→2'),(7→7')-bis(disulfide);13-((1H-indol-3-yl)methyl)-10-(4-aminobutyl)-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-19-(2-(2-hydroxyacetamido)-3-phenylpropanamido)-7-(1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pen;13-((1H-indol-3-yl)methyl)-10-(4-aminobutyl)-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-19-(2-(2-hydroxyacetamido)-3-phenylpropanamido)-7-(1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide;Octreotide Impurity 25;Octreotide Acetate Impurity 17 | | CAS: | 1926163-80-5 | | MF: | C98H132N20O20S4 | | MW: | 2038.49 | | EINECS: | | | Product Categories: | | | Mol File: | 1926163-80-5.mol |  |
| | Octreotide (Dimer, Parallel) Chemical Properties |
| density | 1.42±0.1 g/cm3(Predicted) | | pka | 12.37±0.70(Predicted) | | Sequence | ({d-Phe}-Cys-Phe-{d-Trp}-Lys-Thr-Cys-{L-threoninol})2 (Disulfide bond: Cys2A-Cys2B; Cys7A-Cys7B) |
| | Octreotide (Dimer, Parallel) Usage And Synthesis |
| Uses | Octreotide dimer parallel is a dimer parallel of Octreotide. Octreotide (HY-P0036) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue[1][2]. | | References | [1] D. V. Avdeev, et al. Optimal Method for Disulfide Bond Closure in the Synthesis of Atosiban—Antagonist of Oxytocin Receptors. Russian Journal of Bioorganic Chemistry volume 47, pages1241–1248 (2021)
[2] Wang XX, et al. Effects of octreotide on hepatic glycogenesis in rats with high fat dietinduced obesity. Mol Med Rep. 2017 Jul;16(1):109-118 DOI:10.3892/mmr.2017.6586 |
| | Octreotide (Dimer, Parallel) Preparation Products And Raw materials |
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