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Nanjing Dulai Biotechnology Co., Ltd.
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025-846993838003-8003 18013301590 |
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| Products Intro: |
Product Name:Myristoyl coenzyme A lithium salt
CAS:187100-75-0
Purity:>=80% Package:5mg
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:Myristoyl coenzyme A lithium salt
CAS:187100-75-0
Purity:>=80.0% Package:5MG Remarks:M4414-5MG
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| Company Name: |
BOC Sciences
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16314854226 |
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inquiry@bocsci.com |
| Products Intro: |
Product Name:Myristoyl coenzyme A lithium salt
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| | MYRISTOYL COENZYME A C14:0 LITHIUM SALT Basic information |
| Product Name: | MYRISTOYL COENZYME A C14:0 LITHIUM SALT | | Synonyms: | N-TETRADECANOYL COENZYME A LITHIUM SALT;MYRISTOYL COENZYME A C14:0 LITHIUM SALT;Coenzyme A S-tetradecanoate lithium salt;MYRISTOYL COENZYME A, LITHIUM;myristoyl coenzyme a lithium salt;coenzyme A myristoyl derivative (C14:0), lithium salt;Myristoyl coenzyme A lithium salt >=80.0%;Myristoyl CoA lithium salt | | CAS: | 187100-75-0 | | MF: | C35H63LiN7O17P3S | | MW: | 985.84 | | EINECS: | | | Product Categories: | | | Mol File: | 187100-75-0.mol |  |
| | MYRISTOYL COENZYME A C14:0 LITHIUM SALT Chemical Properties |
| storage temp. | -20°C | | form | Solid | | color | White to off-white |
| | MYRISTOYL COENZYME A C14:0 LITHIUM SALT Usage And Synthesis |
| Uses | Myristoyl coenzyme A lithium is lithium-labeled myristoylated coenzyme A (CoA). Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT). And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms. | | Biochem/physiol Actions | Myristoyl coenzyme A is a combination of coenzyme A and myristate. It serves as a substrate in protein myristoylation, catalyzed by the enzyme N-myristoyl transferase. Myristyolation involves the transfer of the myristoyl group to the glycine residue at the amino-terminal of the protein. | | IC 50 | Human Endogenous Metabolite | | References | [1] Raju RV, et al. Coenzyme A dependent myristoylation and demyristoylation in the regulation of bovine spleen N-myristoyltransferase. Mol Cell Biochem. 1996 May 24;158(2):107-13. DOI:10.1007/BF00225835 |
| | MYRISTOYL COENZYME A C14:0 LITHIUM SALT Preparation Products And Raw materials |
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