- Polygalacin D
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- $0.00 / 25kg
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2024-04-12
- CAS:66663-91-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
- Polygalacin D
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- $0.00 / 5mg
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2023-02-24
- CAS:66663-91-0
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- Polygalacin D
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- $16.00 / 1KG
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2020-03-10
- CAS:66663-91-0
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1kg, 10kg, 50kg
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| | Polygalacin D Basic information |
| Product Name: | Polygalacin D | | Synonyms: | Polygalacin D;Onjisaponin D;Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-2,16,23-trihydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4β,16α)-;Polygalacin D2 | | CAS: | 66663-91-0 | | MF: | C57H92O27 | | MW: | 1209.34 | | EINECS: | | | Product Categories: | | | Mol File: | 66663-91-0.mol |  |
| | Polygalacin D Chemical Properties |
| density | 1.54±0.1 g/cm3 (20 ºC 760 Torr) | | storage temp. | 4°C, protect from light | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 12.76±0.70(Predicted) |
| | Polygalacin D Usage And Synthesis |
| Chemical Properties | White needle crystal. Soluble in water, ethanol, methanol and other solvents, insoluble in petroleum ether, chloroform, ethyl acetate. | | Definition | ChEBI: Polygalacin D is a triterpenoid saponin. It has a role as a metabolite. | | Biological Activity | Polygalacin D (PGD) is a bioactive compound with anticancer and antiproliferative properties isolated from Platycodon grandiflorum. It inhibits the expression of the IAP protein family, including survivin, cIAP-1 and cIAP-2 proteins, and blocks the PI3K/Akt pathway by inhibiting GSK3β, Akt phosphorylation and PI3K expression. It induces apoptosis through the PI3K/Akt pathway. | | target | NOS | COX | PGE | NO | NF-kB |
| | Polygalacin D Preparation Products And Raw materials |
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