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| | 6-Keto prostaglandin f1alpha-d4 Basic information |
| Product Name: | 6-Keto prostaglandin f1alpha-d4 | | Synonyms: | 6-KETO-PROSTAGLANDIN F1ALPHA-3,3,4,4-D4;6-OXO-9ALPHA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC-3,3,4,4-D4 ACID;6-keto Prostaglandin F1α-d4;KFGOFTHODYBSGM-GKZGVFJGSA-N;6-keto Prostaglandin F1α-d4, CAS 82414-64-0;6-Keto prostaglandin f1alpha-d4 | | CAS: | 82414-64-0 | | MF: | C20H34O6 | | MW: | 370.49 | | EINECS: | | | Product Categories: | | | Mol File: | 82414-64-0.mol |  |
| | 6-Keto prostaglandin f1alpha-d4 Chemical Properties |
| solubility | DMF: >100 mg/ml (from 6-keto PGF1a); DMSO: >50 mg/ml (from 6-keto PGF1a); Ethanol: >16 mg/ml (from 6-keto PGF1a); PBS pH 7.2: >3.3 mg/ml (from 6-keto PGF1a |
| | 6-Keto prostaglandin f1alpha-d4 Usage And Synthesis |
| Description | 6-keto Prostaglandin F1α-d4 (6-keto PGF1α-d4) contains four deuterium atoms at the 3, 3'', 4, and 4'' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF1α by GC- or LC-MS. 6-keto PGF1α is the inactive, non-enzymatic hydrolysis product of PGI2. 6-keto PGF1α serves as a useful marker of PGI2 biosynthesis in vivo. When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto PGF1α. | | Uses | 6-keto Prostaglandin F1α-d4 is the deuterium labeled 6-keto Prostaglandin F1α[1]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110 |
| | 6-Keto prostaglandin f1alpha-d4 Preparation Products And Raw materials |
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