- Exifone USP/EP/BP
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- $1.10 / 1g
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2021-07-28
- CAS:52479-85-3
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons min
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| | Exifone Basic information |
| Product Name: | Exifone | | Synonyms: | 3,4,5,2',3',4'-HEXAHYDROXYBENZOPHENONE;(2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)methanone;2,3,3',4,4',5'-HEXAHYDROXYBENZOPHENONE;2,3,4,3',4',5'-HEXAHYDROXY BENZOPHENONE;EXIFONE;(2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)-methanon;4-galloylpyrogallol;adlone | | CAS: | 52479-85-3 | | MF: | C13H10O7 | | MW: | 278.21 | | EINECS: | 257-945-9 | | Product Categories: | Aromatics;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals | | Mol File: | 52479-85-3.mol |  |
| | Exifone Chemical Properties |
| Melting point | 245°C | | Boiling point | 674.6±55.0 °C(Predicted) | | density | 1.759±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 6.99±0.40(Predicted) | | color | Yellow | | Merck | 3915 | | Stability: | Hygroscopic | | CAS DataBase Reference | 52479-85-3(CAS DataBase Reference) |
| Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | RTECS | PC4995000 | | Toxicity | LD50 in rats (g/kg): 0.355 i.p.; 1.425 orally (Gazave) |
| | Exifone Usage And Synthesis |
| Description | Exifone is a nootropic indicated for the treatment of cognitive dysfunctions in geriatric
patients. Its reported clinical efficacy is ascribed to pharmacological activities including
activation of neuronal oxygen and glucose metabolism, free radical scavenging, and
indirect effects on serotonergic and dopaminergic pathways. | | Chemical Properties | yellow amorphous powder | | Originator | Pharmascience (France) | | Uses | Exifone is a nootropic drug and cognitive enhancing agent. Exifone is a free radical scavenger shown to have protective effects againts Exifone has been shown to antagonize amnesias induced by benzodiazepines in mice. | | Preparation | Preparation by condensation of gallic acid with pyrogallol,
? in the presence of zinc chloride at 120° (good yield) or at 145° for 3 h (Nencki reaction);
? in the presence of zinc chloride and phosphorous oxychloride at 80° for 2 h, via Fries rearrangement. | | Definition | ChEBI: (2,3,4-trihydroxyphenyl)-(3,4,5-trihydroxyphenyl)methanone is a member of benzophenones. | | Brand name | Adlone |
| | Exifone Preparation Products And Raw materials |
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