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| | Hyaluronate lyase Basic information |
| Product Name: | Hyaluronate lyase | | Synonyms: | hyaluronate lyase from streptomyces*hyalurolyticu;Lyase, hyaluronate;hyalurolyticus;Hyaluronate Lyase from Streptomyces;Glucuronoglycosaminoglycan lyase;Lyase, glucuronoglycosaminoglycan;Hyaluronate Lyase from Streptococcus pyogenes;HYALURONATE LYASE | | CAS: | 37259-53-3 | | MF: | | | MW: | 0 | | EINECS: | 253-430-8 | | Product Categories: | | | Mol File: | Mol File | ![Hyaluronate lyase Structure]() |
| | Hyaluronate lyase Chemical Properties |
| storage temp. | 2-8°C | | form | lyophilized powder | | color | white to slightly brown | | biological source | Streptomyces sp. (S. hyalurolyticus) | | Specific Activity | ≥8.0units/mg protein (5.0-15.0 mg/mL) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 3-10 | | Storage Class | 11 - Combustible Solids |
| | Hyaluronate lyase Usage And Synthesis |
| Uses | Hyaluronidase from Streptomyces hyalurolyticus has been used:
- in the preparation of DMEM/F-12 (Dulbecco′s modified eagle medium/nutrient mixture F-12) media for the isolation and purification of single cells from dissociated tumour tissue
- as a component of digestion solution for the derivation of germline stem cells from testicular tissue
| | General Description | Hyaluronidase is widely present in nature. In humans, it is present in a number of organs and body fluids. Hyaluronidase is found in the secretions of virus, bacteriophage, fungi and bacteria. It is also present in nematode and leeches secretions. Snakes and scorpions produce hyaluronidase in their venom. Hyaluronidase is also secreted by bees, spiders, wasps, hornets, caterpillars, fishes and lizards. | | Biochem/physiol Actions | Hyaluronate lyase degrades hyaluronate using an elimination reaction to break glycosidic linkages yielding unsaturated disaccharide products. It is important for the diffusion of toxins and proteins produced by S. pyogenes. |
| | Hyaluronate lyase Preparation Products And Raw materials |
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