ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Phosphonate / phosphonate >Triethyl 4-phosphonocrotonate

Triethyl 4-phosphonocrotonate

Request For Quotation
Triethyl 4-phosphonocrotonate Suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Tel: 18210857532 18210857532
Email: jkinfo@jkchemical.com
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Tel: 4006356688 18621169109
Email: market03@meryer.com
Company Name: Alfa Aesar  
Tel: 400-6106006
Email: saleschina@alfa-asia.com
Company Name: Energy Chemical  
Tel: 400-0056266 18918157536;
Email: sales8178@energy-chemical.com
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Tel: 021-54306202 13764082696
Email: info@hanhongsci.com

Triethyl 4-phosphonocrotonate manufacturers
Triethyl 4-phosphonocrotonate Basic information
Product Name:Triethyl 4-phosphonocrotonate
Synonyms:4-PHOSPHONOCROTONIC ACID TRIETHYL ESTER;TRANS-ETHYL-4-(DIETHYLPHOSPHONO)CROTONATE;TRIETHYL 4-PHOSPHONO-2-BUTENOATE;TRIETHYL 4-PHOSPHONOCROTONATE, TECH., 90 %, MIXTURE OF ISOMERS;Triethyl 4-phosphonocrotonate, predominantly trans, 92%;triethyl 4-phosphonocrotonate, cis + trans;triethyl 4-phosphonocrotonate, mixture of isomers;triethyl trans-4-phosphono-2-butenoate
CAS:10236-14-3
MF:C10H19O5P
MW:250.23
EINECS:
Product Categories:C-C Bond Formation;Horner-Wadsworth-Emmons Reagents;Olefination
Mol File:10236-14-3.mol
Triethyl 4-phosphonocrotonate Structure
Triethyl 4-phosphonocrotonate Chemical Properties
Boiling point 135 °C0.4 mm Hg(lit.)
density 1.128 g/mL at 25 °C(lit.)
refractive index n20/D 1.455(lit.)
Fp >230 °F
storage temp. Storage temp. 2-8°C
form Liquid
color Clear light yellow
InChI1S/C10H19O5P/c1-4-13-10(11)8-7-9-16(12,14-5-2)15-6-3/h7-8H,4-6,9H2,1-3H3/b8-7+
InChIKeyLXLODBXSCRTXFG-BQYQJAHWSA-N
SMILESCCOC(=O)\C=C\CP(=O)(OCC)OCC
CAS DataBase Reference10236-14-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39-24/25
WGK Germany 3
HazardClass IRRITANT
HS Code 29319090
Storage Class10 - Combustible liquids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
Triethyl 4-phosphonocrotonate Usage And Synthesis
Chemical PropertiesCLEAR LIGHT YELLOW LIQUID
UsesReactant for:
  • Iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase
  • Stereoselective preparation of C1-C19 fragment of macrolide antibiotic aplyronine A using diastereoselective Nozaki-Hiyama-Kishi coupling reactions
  • Orally bioavailable GPR40 agonist synthesis
  • Synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2
  • Preaparation of mGlu4R agonists
  • Dearomatizing cyclization of nicotinyl-substituted esters and ketones
UsesTriethyl 4-phosphonocrotonate is used as a reactant for iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase, orally bioavailable GPR40 agonist synthesis, preparation of mGlu4R agonists and synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.
reaction suitabilityreaction type: C-C Bond Formation
Triethyl 4-phosphonocrotonate Preparation Products And Raw materials
Raw materialsDiethyl vinylphosphonate-->ethyl 4-bromocrotonate-->Triethyl phosphite-->Ethyl diazoacetate
Tag:Triethyl 4-phosphonocrotonate(10236-14-3) Related Product Information
Triethyl 3-phosphonopropionate Triethyl 4-phosphonobutyrate Triethyl 4-phosphonocrotonate Diethyl ethylphosphonate Ethylphosphonic acid Methylphosphonic acid Methyldiethoxyphosphine Dimethyl methylphosphonate DIETHYL ALLYLPHOSPHONATE Diethyl methylphosphonate Trimethyl 4-phosphonocrotonate Dimethyl ethylphosphonite Dimethyl allylphosphonate Ethyl methylphosphonic acid Dimethyl ethylphosphonate Ethyl hydrogen ethylphosphonate Diethyl ethylphosphonite Allylphosphonic acid