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4-Hydroxy-L-phenylglycine

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Company Name: Shanghai Chiral Chemicals Inc.  Gold
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4-Hydroxy-L-phenylglycine manufacturers

  • Oxfenicine
  • Oxfenicine pictures
  • $40.00
  • 2026-08-22
  • CAS:32462-30-9
  • Purity: 99.60%
  • Supply Ability: 10g
4-Hydroxy-L-phenylglycine Basic information
Product Name:4-Hydroxy-L-phenylglycine
Synonyms:H-PHG(4-HYDROXY)-OH;H-HPG-OH;L-(+)-A-4-HYDROXYPHENYLGLYCINE;L-4-HYDROXYPHENYLGLYCINE;L-(+)-P-HYDROXYPHENYLGLYCINE;4-HYDROXY-L-PHENYLGLYCINE;(S)-AMINO-(4-HYDROXY-PHENYL)-ACETIC ACID;L-(+)-Hydroxy
CAS:32462-30-9
MF:C8H9NO3
MW:167.16
EINECS:251-061-7
Product Categories:Amino ACIDS SERIES
Mol File:32462-30-9.mol
4-Hydroxy-L-phenylglycine Structure
4-Hydroxy-L-phenylglycine Chemical Properties
Melting point ~240 °C (dec.)
Boiling point 365.8±32.0 °C(Predicted)
alpha 158 º (c=1% in 1M HCl)
density 1.396±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Aquous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Water (Slightly)
pka2.15±0.10(Predicted)
form Solid
color White to Off-White
Optical Rotation[α]20/D +158±3°, c = 1% in 1 M HCl
BRN 3589845
Major Applicationpeptide synthesis
InChIInChI=1/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s3
InChIKeyLJCWONGJFPCTTL-ZETCQYMHSA-N
SMILES[C@@H](C1C=CC(O)=CC=1)(N)C(=O)O |&1:0,r|
CAS DataBase Reference32462-30-9(CAS DataBase Reference)
EPA Substance Registry SystemBenzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.S)- (32462-30-9)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
TSCA TSCA listed
HS Code 2922.50.4000
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
SigmaAldrich English
4-Hydroxy-L-phenylglycine Usage And Synthesis
Chemical PropertiesWhite crystalline
Uses4-Hydroxy-L-(+)-2-phenylglycine is a carnitine palmitoyltransferase-1 inhibitor. 4-Hydroxy-L-(+)-2-phenylglycine improves whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistance.
UsesVasodilator.
DefinitionChEBI: The L-enantiomer of 4-hydroxyphenylglycine.
reaction suitabilityreaction type: solution phase peptide synthesis
in vivo

Oxfenicine (150 mg/kg, i.p., once daily for 3 weeks) treatment significantly reduces adiposity in high-fat diet rats[4].

Animal Model:Male Sprague-Dawley rats fed a high-fat (HF) diet[4]
Dosage:150 mg/kg
Administration:intraperitoneal injection (i.p.) once daily for 3 weeks
Result:Reduced whole-body fat oxidation, body weight, adiposity, and improved insulin sensitivity in HF-fed rats.
4-Hydroxy-L-phenylglycine Preparation Products And Raw materials
Tag:4-Hydroxy-L-phenylglycine(32462-30-9) Related Product Information
DL-P-Hydroxyphenylglycine D-4-Hydroxyphenylglycine Methyl ester hydrochloride Methyl 4-nitrobenzoate 4-Hydroxy-D-phenylglycine methyl ester Potassium (R)-((3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino)(4-hydroxyphenyl)acetate 4-Hydroxy-D-(-)-2-phenylglycine D-(-)-A-4-Hydroxyphenylglycine dane salt methyl potassium DL-4-Hydroxyphenylglycine Methyl 2-amino-2-(4-hydroxyphenyl)acetate Glycine L-Phenylglycine N-(4-Hydroxyphenyl)glycine Fmoc-4-hydroxy-D-phenylglycine (S)-4-Carboxy-3-hydroxyphenylglycine Boc-4-hydroxy-D-phenylglycine parahydroxy phenylglycine dane salt N-L-α-Aspartyl-4-hydroxy-D-phenylglycine 1-[(1S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2α-yl] ester L-(p-Hydroxylphenyl)glycine,potassium salt