ethyl 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate 基本信息
| 中文名称 | ethyl 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate |
|---|---|
| 中文同义词 | 4-羟基-7-甲基-1,8-萘啶-3-羧酸乙酯 |
| 英文名称 | ethyl 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate |
| 英文同义词 | ethyl 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate;4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid ethyl ester;Einecs 236-234-7;7-methyl-4-oxo-1H-1,8-naphthyridine-3-carboxylic acid ethyl ester;ethyl 7-methyl-4-oxo-1H-1,8-naphthyridine-3-carboxylate;1,8-Naphthyridine-3-carboxylic acid, 4-hydroxy-7-methyl-, ethyl ester;Nalidixic Acid EP Impurity B |
| CAS号 | 13250-96-9 |
| 分子式 | C12H12N2O3 |
| 分子量 | 232.24 |
| EINECS号 | 2362347 |
| 相关类别 | |
| Mol文件 | 13250-96-9.mol |
| 结构式 |  |
ethyl 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate 性质
| 熔点 | 272-273 °C |
|---|---|
| 沸点 | 350.5±37.0 °C(Predicted) |
| 密度 | 1.296±0.06 g/cm3(Predicted) |
| 酸度系数(pKa) | 2.83±0.50(Predicted) |
化学性质
油状液体。用途
萘啶酸的中间体。生产方法
用2-甲基吡啶以氨基钠胺化，生成5-氨基-2-甲基吡啶，然后与原甲酸三乙酯及丙二酸二乙酯缩合得[（5-甲基-2-吡啶基）氨基]亚甲基丙二酸二乙酯，将后者在加热下环合即得该品。