| Company Name: |
OPULENT PHARMA
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| Tel: |
+91-9106692785 +91-9106692785 |
| Email: |
info@opulentpharma.com |
| Products Intro: |
Product Name:Abacavir Related Compound D
CAS:1443421-69-9
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| | Abacavir Related CoMpound D Basic information |
| Product Name: | Abacavir Related CoMpound D | | Synonyms: | Abacavir Related CoMpound D;N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine;Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine;Abacavir EP Impurity B;O-Pyrimidine Derivative Abacavir (USP);6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(2,5-diamino-6-chloropyrimidin-4-yl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine;9H-Purine-2,6-diamine, N6-cyclopropyl-9-[(1R,4S)-4-[[(2,5-diamino-6-chloro-4-pyrimidinyl)oxy]methyl]-2-cyclopenten-1-yl]-;Abacavir Impurity D | | CAS: | 1443421-69-9 | | MF: | C18H21ClN10O | | MW: | 428.88 | | EINECS: | | | Product Categories: | | | Mol File: | 1443421-69-9.mol |  |
| | Abacavir Related CoMpound D Chemical Properties |
| Boiling point | 830.1±75.0 °C(Predicted) | | density | 1.90±0.1 g/cm3(Predicted) | | pka | 4.86±0.10(Predicted) |
| WGK Germany | 3 | | HS Code | 2933599550 |
| | Abacavir Related CoMpound D Usage And Synthesis |
| Uses | Abacavir 5’-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. |
| | Abacavir Related CoMpound D Preparation Products And Raw materials |
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