| Company Name: |
MedChemexpress LLC
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021-58955995 |
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sales@medchemexpress.cn |
| Products Intro: |
Product Name:Diperodon (hydrochloride)
CAS:537-12-2
Purity:>98% Package:500RMB/100mg
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| | DIPERODON HYDROCHLORIDE Basic information |
| Product Name: | DIPERODON HYDROCHLORIDE | | Synonyms: | 3-piperidino-1,2-propanedioldicarbanilatehydrochloride;diothanehydrochloride;Diperodon HCl;3-(1-PIPERIDINYL)-1,2-PROPANEDIOL BIS(PHENYLCARBAMATE);3-[1-PIPERIDINYL]-1,2-PROPANEDIOL BIS[PHENYLCARBAMATE] HYDROCHLORIDE;DIPERODON HYDROCHLORIDE;1,2-propanediol,3-(1-piperidinyl)-,bis(phenylcarbamato)(ester),monohydroc;1,2-propanediol,3-piperidino-,dicarbanilate,hydrochloride | | CAS: | 537-12-2 | | MF: | C22H28ClN3O4 | | MW: | 433.93 | | EINECS: | 208-659-8 | | Product Categories: | TANTUM | | Mol File: | 537-12-2.mol |  |
| | DIPERODON HYDROCHLORIDE Chemical Properties |
| Melting point | 193-201°C | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | Methanol (Slightly) | | color | White |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | RTECS | TZ1101000 |
| | DIPERODON HYDROCHLORIDE Usage And Synthesis |
| Originator | Diothane Hydrochloride,HMR | | Uses | analgesic, antipyretic, antiinflammatory | | Uses | Diperodon Hydrochloride is an inhibitor of ebola virus (EBOV) and marburg virus (MARV) by an antiviral activity of the G protein-coupled receptor (GPCR) antagonist. | | Manufacturing Process | 15.0 g phenylisocyanate in 100 ml of anhydrous ether are added to 10 g of N-
(1,2-dihydroxypropyl)-piperidine (prepared from glycide and piperidine) and
the solution boiled for two hours, after which it is cooled and saturated with
dry hydrogen chloride gas. The ether layer is then decanted off and the
remaining insoluble product is dissolved in a hot mixture of acetone and ethyl
acetate which on cooling precipitates white crystals of the hydrochloride of the
ester of 1,2-propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate); MP 197°-
198°C. A base form may be prepared by adding an equivalent of triethyl
amine. | | Therapeutic Function | 1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate)
(ester), hydrochloride |
| | DIPERODON HYDROCHLORIDE Preparation Products And Raw materials |
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