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| | 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Basic information |
| Product Name: | 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE | | Synonyms: | 2,2,2-Trifluoroethyl 4-toluenesulphonate 98%;2,2,2-Trifluoroethyl4-toluenesulphonate98%;p-Toluenesulphonic acid 2,2,2-trifluoroethyl ester;4-Toluenesulfonic acid 2,2,2,-trifluoroethyl ester;Trifluoroethyltosylate;4-Methylbenzenesulfonic acid 2,2,2-trifluoroethyl ester;p-Methylbenzenesulfonic acid 2,2,2-trifluoromethyl;TRIFLUORETHYLTOSYLATE | | CAS: | 433-06-7 | | MF: | C9H9F3O3S | | MW: | 254.23 | | EINECS: | 207-085-5 | | Product Categories: | Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry;Organic Building Blocks;Sulfur Compounds;Tosylates;API intermediates;blocks;BuildingBlocks;FluoroCompounds | | Mol File: | 433-06-7.mol |  |
| | 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Chemical Properties |
| Melting point | 36-38 °C(lit.) | | Boiling point | 87-92 °C0.1 mm Hg(lit.) | | density | 1 g/cm3 | | Fp | >230 °F | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Chloroform (Sparingly), Methanol (Sparingly) | | form | Solid | | color | White to Off-White | | Sensitive | Moisture Sensitive | | BRN | 2699394 | | Stability: | Hygroscopic | | InChIKey | IGKCQDUYZULGBM-UHFFFAOYSA-N | | CAS DataBase Reference | 433-06-7(CAS DataBase Reference) | | NIST Chemistry Reference | Ethanol, 2,2,2-trifluoro-, 4-methylbenzenesulfonate(433-06-7) | | EPA Substance Registry System | Ethanol, 2,2,2-trifluoro-, 4-methylbenzenesulfonate (433-06-7) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | TSCA | T | | HazardClass | IRRITANT | | HS Code | 29049090 |
| | 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Usage And Synthesis |
| Chemical Properties | WHITE CRYSTALLINE SOLID | | Uses | 2,2,2-Trifluoroethyl Tosylate is a trifluoroethylation agent used in the preparation of 2,2,2-trifluoroethyl phenyl sulfone, a potential 2,2,2-trifluoroethyl pronucleophile. | | Synthesis | 2,2,2-Trifluoroethyl p-Toluenesulfonate is easily prepared by treating 2,2,2-trifluoroethanol with p-Toluenesulfonyl Chloride in pyridine or in aqueous acetone containing NaOH.
| | Precautions |
Quite stable; can be handled without any special technique and stored at room temperature; use in a fume hood.
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| | 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Preparation Products And Raw materials |
| Preparation Products | Benzene, [(2,2,2-trifluoroethoxy)methyl]--->Bicyclo[2.2.1]heptane, 2-(2,2-difluoroethenyl)--->2,2,2-TRIFLUOROETHYL METHYL ETHER-->Ethane, 1,1,1-trifluoro-2-(methylthio)--->Ethanone, 1-[3-(2,2,2-trifluoroethoxy)phenyl]- |
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