MRTX-1719 manufacturers
- MRTX-1719
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- $8.00 / 1kg
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2024-04-24
- CAS:2630904-45-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | MRTX-1719 Basic information |
| Product Name: | MRTX-1719 | | Synonyms: | Benzonitrile, 2-[4-[4-(aminomethyl)-1,2-dihydro-1-oxo-6-phthalazinyl]-1-methyl-1H-pyrazol-5-yl]-4-chloro-6-(cyclopropyloxy)-3-fluoro-, (2R)-;MRTX-1719,CRC,Histone Methyltransferase,NSCLC,Inhibitor,MTA,MRTX1719,MRTX 1719,inhibit,PRMT5;2-[4-[4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl]-1-methyl-5-pyrazolyl]-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile;(2R)-2-(4-(4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile | | CAS: | 2630904-45-7 | | MF: | C23H18ClFN6O2 | | MW: | 464.89 | | EINECS: | | | Product Categories: | | | Mol File: | 2630904-45-7.mol |  |
| | MRTX-1719 Chemical Properties |
| density | 1.58±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 11.37±0.40(Predicted) |
| | MRTX-1719 Usage And Synthesis |
| Biological Activity | MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAPDEL SDMA cells[1]. | | References | [1]. Targeting the genetic and immunological drivers of cancer. |
| | MRTX-1719 Preparation Products And Raw materials |
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