エチルホスホロジクロリダート(1498-51-7)

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エチルホスホロジクロリダート 製品概要
化学名:エチルホスホロジクロリダート
英語化学名:Ethyl dichlorophosphate
别名:Ethoxydichlorophosphine oxide;Ethyl phosphoric dichloride;Ethoxyphosphoryl dichloride;Ethoxyphosphorylchloride;Ethyl dichloridophosphate;ethylesterdichlorid;Ethylphosphoric acid dichloride;ethylphosphoricaciddichloride
CAS番号:1498-51-7
分子式:C2H5Cl2O2P
分子量:162.94
EINECS:216-099-0
カテゴリ情報:Phospholipids - 13C & 2H;Phosphorylating and Phosphitylating Agents;Building Blocks;Chemical Synthesis;Organic Building Blocks;Phosphorus Compounds;Phosphorus Halides
Mol File:1498-51-7.mol
エチルホスホロジクロリダート
エチルホスホロジクロリダート 物理性質
融点 -42.5 °C
沸点 60-65 °C10 mm Hg(lit.)
比重(密度) 1.373 g/mL at 25 °C(lit.)
屈折率 n20/D 1.434(lit.)
闪点 >230 °F
貯蔵温度 Inert atmosphere,Room Temperature
外見 Liquid
Clear colorless to pale brown
CAS データベース1498-51-7(CAS DataBase Reference)
NISTの化学物質情報Ethyl dichlorophosphate(1498-51-7)
EPAの化学物質情報Ethyl dichlorophosphate (1498-51-7)
安全性情報
主な危険性 T+,C,Xi
Rフレーズ 26-34-22
Sフレーズ 26-28-36/37/39-45
RIDADR UN 3390 6.1/PG 1
WGK Germany 3
RTECS 番号TD4390000
国連危険物分類 8
容器等級 III
HSコード 29209090
有毒物質データの1498-51-7(Hazardous Substances Data)
MSDS Information
ProviderLanguage
Ethyl phosphorodichloridate English
SigmaAldrich English
ACROS English
エチルホスホロジクロリダート Usage And Synthesis
外観無色~ほとんど無色透明液体
化学的特性Light Yellow Liquid
使用Ethyl Dichlorophosphate is an intermediate used in the synthesis of b-D-2'-deoxy-2'-a-fluoro-2'-b-C-methyluridine nucleotide prodrug (PSI-7977) for treatment of hepatitis C virus. It is also used to prepare dialkylphosphocholines with antiprotozoal, antifungal and antitumor activities.
一般的な説明Ethyl dichlorophosphate is strongly irritating to skin. Ethyl dichlorophosphate may cause visible destruction or irreversible alterations in human skin tissue at the site of contact. Ethyl dichlorophosphate is very toxic by ingestion, inhalation, or by skin absorption. Ethyl dichlorophosphate may be combustible though Ethyl dichlorophosphate may require some effort to ignite.
空気と水の反応Reacts with water to form hydrogen chloride(hydrochloric acid)
反応プロフィールOrganophosphates, such as Ethyl dichlorophosphate, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
健康ハザードInhalation of vapor irritates nose and throat. Contact with liquid causes severe burns of eyes and skin. Ingestion causes severe burns of mouth and stomach.
安全性プロファイルA corrosive material that is very toxic to tissue. A severe eye, skin, and mucous membrane irritant. When heated to decomposition it emits very toxic fumes of Cland POx.
Tags:1498-51-7