- Obtusin
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- $40.00
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2026-07-15
- CAS:70588-05-5
- Purity: 99.27%
- Supply Ability: 10g
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| | 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione Basic information |
| Product Name: | 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione | | Synonyms: | 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione;1,7-Dihydroxy-2,3,8-trimethoxy-6-methyl-9,10-anthraquinone;Obtusin,1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione;1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dioneObtusin;9,10-Anthracenedione, 1,7-dihydroxy-2,3,8-trimethoxy-6-methyl-;1-Carboxy-3;Obtusin | | CAS: | 70588-05-5 | | MF: | C18H16O7 | | MW: | 344.32 | | EINECS: | | | Product Categories: | | | Mol File: | 70588-05-5.mol |  |
| | 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione Chemical Properties |
| Melting point | 244.5-246.0 °C | | Boiling point | 614.9±55.0 °C(Predicted) | | density | 1.409±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 6.16±0.20(Predicted) | | color | Yellow to orange |
| | 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione Usage And Synthesis |
| Uses | Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15 μM. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1]. | | Definition | ChEBI: Obtusin is a dihydroxyanthraquinone. | | References | [1] Paudel P, et al. In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds. ACS Omega. 2019 Sep 18;4(14):16139-16152. DOI:10.1021/acsomega.9b02328 |
| | 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione Preparation Products And Raw materials |
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