| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:DNA-PK Inhibitor IV
CAS:70362-07-1
Purity:98% Package:1G;10G;100G Remarks:DNA-PK inhibitor IV is an inhibitor of DNA-dependent protein kinase (DNA-PK). It also inhibits the phosphatidylinositol 3-kinase (PI3K) isoforms p110β, p110δ, and p110γ but not p110α or class II PI3Ks
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:DNA-PK Inhibitor IV
CAS:70362-07-1
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
Wuxi Kehua Biological Technology Co., Ltd.
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| Tel: |
0510-0510-86838766 |
| Email: |
2258830676@qq.com |
| Products Intro: |
Product Name:2-hydroxy-4-morpholinobenzaldehyde
CAS:70362-07-1
Purity:95.0% Package:10g;25g;50g;100g;500g;1kg;10kg
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| | 2-hydroxy-4-Morpholinobenzaldehyde Basic information |
| | 2-hydroxy-4-Morpholinobenzaldehyde Chemical Properties |
| Boiling point | 401.3±45.0 °C(Predicted) | | density | 1.272±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 33 mg/ml,DMSO: 33 mg/ml,DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml | | pka | 8.48±0.10(Predicted) |
| | 2-hydroxy-4-Morpholinobenzaldehyde Usage And Synthesis |
| Description | DNA-PK inhibitor IV is an inhibitor of DNA-dependent protein kinase (DNA-PK) with an IC50 value of 400 nM for the DNA-PK-dependent phosphorylation of a p53 peptide substrate. It also inhibits the phosphatidylinositol 3-kinase (PI3K) isoforms p110β, p110δ, and p110γ (IC50s = 2.8, 5.1, and 37 nM, respectively) but not p110α (IC50 = ~10 μM) or class II PI3Ks, PI4Kβ, ATM, ATR, mTOR, CK2, or GRK2 (IC50s = >50 μM). It enhances radiation-induced cytotoxicity of HCT116 cells when used at a concentration of 100 μM. |
| | 2-hydroxy-4-Morpholinobenzaldehyde Preparation Products And Raw materials |
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