5-(1,1-二甲基庚基)-2-[5-羟基-2-(3-羟基丙基)环己基]苯酚 基本信息
| 中文名称 | 5-(1,1-二甲基庚基)-2-[5-羟基-2-(3-羟基丙基)环己基]苯酚 |
|---|---|
| 中文同义词 | 5-(1,1-二甲基庚基)-2-[5-羟基-2-(3-羟基丙基)环己基]苯酚;(-)-CP 55,940;化合物 T19695 |
| 英文名称 | 5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol |
| 英文同义词 | CP 55,940;(-)-CIS-3-[2-HYDROXY-4-(1,1-DIMETHYLHEPTYL)PHENYL]-TRANS-4-(3-HYDROXYPHENYL) CYCLOHEXANOL;(-)-CIS-3-[2-HYDROXY-4-(1,1-DIMETHYLHEPTYL)PHENYL]-TRANS-4-(3-HYDROXYPROPYL)CYCLOHEXANOL;(-)-Cis-3-[2-Hydroxy-4-(1,1-Di;(1R)-3β-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-4α-(3-hydroxypropyl)cyclohexane-1β-ol;3β-[4-(1,1-Dimethylheptyl)-2-hydroxyphenyl]-4α-(3-hydroxypropyl)cyclohexan-1β-ol;5-(1,1-DIMETHYLHEPTYL)-2-[(1R,2R,5R)-5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL;2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-Methyloctan-2-yl)phenol |
| CAS号 | 83002-04-4 |
| 分子式 | C24H40O3 |
| 分子量 | 376.57 |
| EINECS号 | |
| 相关类别 | 试剂盒-细胞分析试剂盒;Cannabinoid receptor;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pfizer Compounds;Pharmaceuticals |
| Mol文件 | 83002-04-4.mol |
| 结构式 | ![5-(1,1-二甲基庚基)-2-[5-羟基-2-(3-羟基丙基)环己基]苯酚 结构式](CAS/GIF/83002-04-4.gif) |
5-(1,1-二甲基庚基)-2-[5-羟基-2-(3-羟基丙基)环己基]苯酚 性质
| 熔点 | 65-68 °C |
|---|---|
| 沸点 | 494.4±45.0 °C(Predicted) |
| 密度 | 1.026±0.06 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | DMSO：15 mg/mL，可溶 |
| 形态 | 固体 |
| 酸度系数(pKa) | 10.25±0.40(Predicted) |
| 旋光度 (Optical Rotation) | [α]/D -24 to -30°, c =0.2 in chloroform-d |
| InChI | 1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1 |
| InChIKey | YNZFFALZMRAPHQ-SYYKKAFVSA-N |
| SMILES | CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 |
用途
CP 55,940 is a cannabinoid agonist which is considerably more potent than 螖9-THC in both behavioral tests and receptor binding assays. Displays high and roughly equal affinity for both central and per
ipheral cannabinoid receptors (Ki = 0.6 - 5.0 and 0.7 - 2.6 nM at CB1 and CB2 respectively; EC50 values are 0.2, 0.3 and 5 nM at CB1, CB2 and GRP55 respectively).
Controlled substance.安全信息
| 安全说明 | 22-24/25 |
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| WGK Germany | 3 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 特异性靶器官毒性-一次接触，类别3 |
| 提供商 | 语言 |
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英文
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