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N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolid

N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-66670886
Email: info@dakenchem.com
Products Intro: Product Name:N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea
CAS:39236-46-9
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:39236-46-9
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418679
Email: info@tnjchem.com
Products Intro: Product Name:Imidazolidinyl Urea
CAS:39236-46-9
Purity:99.9% Package:1KG;5USD
Company Name: Tianjin Zhongxin Chemtech Co., Ltd.
Tel: 022-66880623
Email: sales@tjzxchem.com
Products Intro: Product Name:N,N-methylenebis N-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea
CAS:39236-46-9
Purity:— Package:25kgs fiber drum
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Imidazolidinyl Urea
CAS:39236-46-9
Purity:98% Package:25g/100g

N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea manufacturers

  • Imidazolidinyl Urea
  • $20.00 / KG
  • 2021-12-03
  • CAS:39236-46-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 200tons/ year
  • Imidazolidinyl Urea
  • $10.00 / Kg/Drum
  • 2021-12-01
  • CAS:39236-46-9
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 10 ton
  • Imidazolidinyl urea
  • $10.00 / KG
  • 2021-11-09
  • CAS:39236-46-9
  • Min. Order: 1KG
  • Purity: 98.0%
  • Supply Ability: 10tons/month
N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea Basic information
Product Name:N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea
Synonyms:LABOTEST-BB LT00772046;IMIDAZOLIDINYL UREA;IMIDUREA;1,1-METHYLENEBIS[3-[3-(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL]UREA];N,N''-METHYLENEBIS[N'-[3-(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL]UREA];N,N''-METHYLENEBIS[N-[3-(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL]UREA];germall115;Imidurea (200 mg)
CAS:39236-46-9
MF:C11H16N8O8
MW:388.29
EINECS:254-372-6
Product Categories:Cosmetics
Mol File:39236-46-9.mol
N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea Structure
N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea Chemical Properties
Melting point 141-143℃
Boiling point 514.04°C (rough estimate)
density 1.4245 (rough estimate)
refractive index 1.6910 (estimate)
storage temp. 2-8°C
solubility Soluble in water and in glycerol, but insoluble in almost all organic solvents.
pka7.41±0.10(Predicted)
form Liquid
color Clear
Water Solubility soluble
Merck 14,4916
Stability:Stable.
InChIKeyZCTXEAQXZGPWFG-UHFFFAOYSA-N
CAS DataBase Reference39236-46-9(CAS DataBase Reference)
EPA Substance Registry SystemImidurea (39236-46-9)
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26-36
WGK Germany 2
RTECS YT7365000
TSCA Yes
HS Code 29332990
MSDS Information
N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea Usage And Synthesis
DescriptionImidazolidinyl urea, a formaldehyde releaser, is mainly contained in cosmetics and liquid soaps.
Chemical PropertiesN,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea is solid with a mild odour
Chemical PropertiesImidurea is a white, free-flowing odorless powder.
Usesimidazolidinyl urea is one of the most commonly used anti-bacterial preservatives given its low sensitizing potential. In 2010, it was the tenth most frequently used preservative in the united States (parabens ranged from first to sixth place). generally, imidazolidinyl urea is not used alone but as a copreservative with parabens for broad-spectrum activity. Although it may yield low levels of formaldehyde when subjected to destructive methods-such as exposure to high temperatures-under normal use conditions, there is no detection of free formaldehyde release. of all the formaldehydereleasing preservatives, imidazolidinyl urea is the one least likely to cause skin sensitization and allergic reactions.
UsesAntimicrobial
UsesAntimicrobial preservative in cosmetics and topical pharmaceutical preparations.
Production MethodsImidurea is produced by the condensation of allantoin with formaldehyde.
Pharmaceutical ApplicationsN,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea is a broad-spectrum antimicrobial preservative used in cosmetics and topical pharmaceutical formulations; typical concentrations used are 0.03–0.5% w/w. It is effective between pH 3–9 and is reported to have synergistic effects when used with parabens.
Contact allergensImidazolidinyl urea, a formaldehyde releaser related to diazolidinyl urea (see above), is used as an antimicrobial agent very active against Gram-positive and Gram-negative bacteria, used as a synergist in combination with para- bens. It is used as a preservative in aqueous products, mainly in cosmetics, toiletries, and liquid soaps.
SafetyImidurea is widely used in cosmetics and topical pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material. However, there have been some reports of contact dermatitis associated with imidurea, although these are relatively few considering its widespread use in cosmetics. Although imidurea releases formaldehyde, it does not appear to be associated with cross-sensitization with formaldehyde or other formaldehyde-releasing compounds.
LD50 (mouse, oral): 7.2 g/kg
LD50 (rabbit, skin): > 8 g/kg
LD50 (rat, oral): 11.3 g/kg
storageImidurea is hygroscopic and should be stored in a well-closed container in a cool, dry place.
IncompatibilitiesN,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea is incompatible with strong oxidants. It is compatible with other preservatives including sorbic acid and quaternary ammonium compounds. It is also compatible with other pharmaceutical and cosmetic excipients including proteins, nonionic surfactants, and lecithin.
Regulatory StatusIncluded in the FDA Inactive Ingredients Database (topical preparations). Accepted for use in cosmetics in Europe and the USA. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea Preparation Products And Raw materials
Tag:N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea(39236-46-9) Related Product Information
1,1,7-trichloro-1-hepten-3-one Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride Acetylferrocene PHENYLUREA 1-Bromonaphthalene 2,2'-Bipyridine 4-tert-Butylbenzoic acid Urea Allantoin Diazolidinyl Urea ALCLOXA 1-METHYLHYDANTOIN N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea 2-Imidazolidone