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| | licopyranocoumarin Basic information |
| Product Name: | licopyranocoumarin | | Synonyms: | licopyranocoumarin;(+)-3-(2,4-Dihydroxyphenyl)-8-(hydroxymethyl)-6,7-dihydro-8-methyl-5-methoxy-2H,8H-benzo[1,2-b:5,4-b']dipyran-2-one;3-(2,4-Dihydroxyphenyl)-8-(hydroxymethyl)-5-methoxy-8-methyl-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one | | CAS: | 117038-80-9 | | MF: | C21H20O7 | | MW: | 384.38 | | EINECS: | | | Product Categories: | | | Mol File: | 117038-80-9.mol |  |
| | licopyranocoumarin Chemical Properties |
| Boiling point | 675.3±55.0 °C(Predicted) | | density | 1.397±0.06 g/cm3(Predicted) | | pka | 8.89±0.40(Predicted) |
| | licopyranocoumarin Usage And Synthesis |
| Uses | Licopyranocoumarin is an isoflavonoid that shows CYP3A4 inhibitory activity with an IC50 of 32 μM. Licopyranocoumarin has potent neuroprotective activities[1]. | | Definition | ChEBI: Licopyranocoumarin is an isoflavonoid and an organic hydroxy compound. | | IC 50 | CYP3A4: 32 μM (IC50) | | References | [1] Takahiro Fujimaki, et al. Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease. PLoS One. 2014 Jun 24;9(6):e100395. DOI:10.1371/journal.pone.0100395
[2] Sachiko Tsukamoto, et al. CYP3A4 inhibitors isolated from Licorice. Biol Pharm Bull. 2005 Oct;28(10):2000-2. DOI:10.1248/bpb.28.2000 |
| | licopyranocoumarin Preparation Products And Raw materials |
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