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Apigenin

Apigenin Suppliers list
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
Email: fandachem@gmail.com
Products Intro: Product Name:Apigenin
CAS:520-36-5
Package:as in COA
Company Name: Capot Chemical Co.,Ltd.
Tel: +86 (0)571-855 867 18
Email: sales@capotchem.com
Products Intro: Product Name:Apigenin
CAS:520-36-5
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Email: Abel@chembj.com
Products Intro: Product Name:Apigenin
CAS:520-36-5
Purity:10:01 Package:120/KG
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Apigenin
CAS:520-36-5
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:520-36-5
Purity:99% Package:500G;1KG;5KG;25KG

Lastest Price from Apigenin manufacturers

  • Apigenin
  • US $10.00 / KG
  • 2018-10-22
  • CAS:520-36-5
  • Min. Order: 5G
  • Purity: ≥99.5%
  • Supply Ability: 1000 kg/week
  • Apigenin
  • US $100.00 / KG
  • 2018-07-27
  • CAS:520-36-5
  • Min. Order: 25KG
  • Purity: 99%
  • Supply Ability: 10tons
Apigenin Basic information
Description References
Product Name:Apigenin
Synonyms:4',5,7-Trihydroxyflavone 5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-on 5,7,4'-Trihydroxyflavone;APIGENIN;CHAMOMILE;4',5,7-TRIHYDROXYFLAVONE;4,5,7-TRIHYDROXYFLAVONE;4',5,7-TRIHYROXYFLAVONE;5,7,4'-TRIHYDROXYFLAVONE;5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE
CAS:520-36-5
MF:C15H10O5
MW:270.24
EINECS:208-292-3
Product Categories:Tri-substituted Flavones;Biochemistry;Flavonoids;Natural Plant Extract;Inhibitors;Protein Kinase;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product;Signalling;CITRIMORE;Plant extract;pyridine series
Mol File:520-36-5.mol
Apigenin Structure
Apigenin Chemical Properties
Melting point >300 °C(lit.)
Boiling point 333.35°C (rough estimate)
density 1.2319 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. −20°C
solubility DMSO: 27 mg/mL
form powder
color yellow
Merck 14,730
BRN 262620
InChIKeyKZNIFHPLKGYRTM-UHFFFAOYSA-N
CAS DataBase Reference520-36-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS LK9276000
10
HS Code 29329985
Hazardous Substances Data520-36-5(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Apigenin Usage And Synthesis
DescriptionApigenin (chemically known as 4′, 5, 7-trihydroxyflavone, with molecular formula C15H10O5) is with molecular weight of 270.24. It is a naturally occurring plant flavone and is abundantly present in common fruits such as grapefruit, plant-derived beverages, and vegetables such as parsley, onions, oranges, tea, chamomile, wheat sprouts and in some seasonings.
Apigenin has gained particular interest in recent years as a beneficial and health promoting agent owing to its low intrinsic toxicity and its striking effects on normal versus cancer cells, compared with other structurally-related flavonoids. It has been increasingly recognized as a cancer and tumor  chemopreventive agent (for breast cancer, cervical cancer, colon cancer, hematologic cancer, lung cancer, ovaria cancer, prostate cancer, skin cancer, thyroid cancer, endometrial cancer, gastric cancer, liver cancer, adrenal cortical cancer, leukemia, and neuroblastoma) owing to its anti-inflammatory, antioxidant and anticancer properties.
References[1] Sanjeev Shukla, Sanjay Gupta (2010) Apigenin: a promising molecule for cancer prevention, 27, 962-978.
[2] https://en.wikipedia.org/wiki/Apigenin
[3] http://bodynutrition.org/apigenin/
Chemical PropertiesPale Yellow Crystalline Solid
Usesantispasmodic, antineoplastic, topoisomerase I inhibitor
UsesInduces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tum or cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.
UsesHas been used to dye Cr mordanted wool yellow. The color is fast to soap.
Biological ActivityProtein kinase inhibitor. Suppresses tumor-promoting effects of TPA and exhibits antiproliferative activity in human breast cancer cells (IC 50 values are 59.44 and 31.15 μ M at 24 and 72 hrs respectively). Activates both the intrinsic and extrinsic apoptotic pathways and displays anti-inflammatory, hypotensive, antispasmodic and antioxidant properties in vivo .
Purification MethodsCrystallise it from aqueous pyridine or aqueous EtOH. It dyes wool yellow when mixed with Cr ions. [Beilstein 18 H 181, 18 I 396, 18 II 178, 18 III/IV 2682, 18/4 V 574.]
Apigenin Preparation Products And Raw materials
Tag:Apigenin(520-36-5) Related Product Information
2-(Hydroxymethyl)phenyl-beta-D-glucopyranoside Quercetin dihydrate Icariin Riboflavin Diosmin APIGENIN-7-NEOHESPERIDOSIDE hplc,apigenin 7-O-hesperidoside 5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE ARTEMISININ 3,7,3',4'-TETRAMETHYLGOSSYPETIN Quercetin Myricitrin CHRYSOERIOL 3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE EUPATORIN-5-METHYL ETHER Myricetin 3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE Rutin AVICULARIN