| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:4-Phenyl-1,2,3-thiadiazole, 98%
CAS:25445-77-6
Purity:98% Package:1G;250MG;5G
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| Company Name: |
Alfa Aesar
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| Tel: |
400-6106006 |
| Email: |
saleschina@alfa-asia.com |
| Products Intro: |
Product Name:4-Phenyl-1,2,3-thiadiazole
CAS:25445-77-6
Package:250Mg Remarks:L20197
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| | 4-PHENYL-1,2,3-THIADIAZOLE Basic information |
| Product Name: | 4-PHENYL-1,2,3-THIADIAZOLE | | Synonyms: | 4-PHENYL-1,2,3-THIADIAZOLE;BUTTPARK 91\16-70;4-Phenyl-1,2,3-thiadiazole ,98%;4-phenylthiadiazole;1,2,3-Thiadiazole, 4-phenyl- | | CAS: | 25445-77-6 | | MF: | C8H6N2S | | MW: | 162.21 | | EINECS: | 636-735-4 | | Product Categories: | | | Mol File: | 25445-77-6.mol |  |
| | 4-PHENYL-1,2,3-THIADIAZOLE Chemical Properties |
| Melting point | 78°C | | Boiling point | 100°C 1,5mm | | density | 1.241±0.06 g/cm3(Predicted) | | Fp | 100°C/1.5mm | | storage temp. | Store at -20°C | | solubility | DMF: 3 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml | | form | A crystalline solid | | pka | -4.23±0.22(Predicted) | | BRN | 119480 |
| Hazard Codes | Xi | | Safety Statements | 22-24/25 | | HazardClass | IRRITANT | | HS Code | 29420000 |
| Provider | Language |
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ALFA
| English |
| | 4-PHENYL-1,2,3-THIADIAZOLE Usage And Synthesis |
| Description | Cytochrome P450 (CYP450) enzymes are a superfamily of oxidative catalysts important in the biosynthesis and metabolism of a wide range of endogenous molecules as well as the metabolism of xenobiotics. For example, CYP2B4 metabolizes substituted amines, CYP2E1 metabolizes various alcohols and halogenated alkenes, and CYP1A2 catalyzes the oxygenation of aromatic compounds and polycyclic hydrocarbons. 4-phenyl-1,2,3-Thiadiazole is, at 100 μM, a selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1), but not others (CYP1A2), with inactivation occurring in a mechanism-based manner. 1,2,3-Thiadiazole compounds and their derivatives, including 4-phenyl-1,2,3-thiadiazole, are also commonly used as fungicides, herbicides, and plant growth regulators. | | Chemical Properties | Off-white to light brown solid | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 28, p. 442, 1985 DOI: 10.1021/jm00382a009 |
| | 4-PHENYL-1,2,3-THIADIAZOLE Preparation Products And Raw materials |
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