4-PHENYL-1,2,3-THIADIAZOLE

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Products Intro: Product Name:4-Phenyl-1,2,3-thiadiazole
CAS:25445-77-6
Purity:0.97 Package:mgs,gs,kgs Remarks:A877588
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Products Intro: Product Name:4-Phenyl-1,2,3-thiadiazole, 98%
CAS:25445-77-6
Purity:98% Package:1G;250MG;5G
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Products Intro: Product Name:4-PHENYL-1,2,3-THIADIAZOLE
CAS:25445-77-6
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Products Intro: Product Name:4-Phenyl-1,2,3-thiadiazole
CAS:25445-77-6
Package:250Mg Remarks:L20197
4-PHENYL-1,2,3-THIADIAZOLE Basic information
Product Name:4-PHENYL-1,2,3-THIADIAZOLE
Synonyms:4-PHENYL-1,2,3-THIADIAZOLE;BUTTPARK 91\16-70;4-Phenyl-1,2,3-thiadiazole ,98%;4-phenylthiadiazole;1,2,3-Thiadiazole, 4-phenyl-
CAS:25445-77-6
MF:C8H6N2S
MW:162.21
EINECS:636-735-4
Product Categories:
Mol File:25445-77-6.mol
4-PHENYL-1,2,3-THIADIAZOLE Structure
4-PHENYL-1,2,3-THIADIAZOLE Chemical Properties
Melting point 78°C
Boiling point 100°C 1,5mm
density 1.241±0.06 g/cm3(Predicted)
Fp 100°C/1.5mm
storage temp. Store at -20°C
solubility DMF: 3 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka-4.23±0.22(Predicted)
BRN 119480
Safety Information
Hazard Codes Xi
Safety Statements 22-24/25
HazardClass IRRITANT
HS Code 29420000
MSDS Information
ProviderLanguage
ALFA English
4-PHENYL-1,2,3-THIADIAZOLE Usage And Synthesis
DescriptionCytochrome P450 (CYP450) enzymes are a superfamily of oxidative catalysts important in the biosynthesis and metabolism of a wide range of endogenous molecules as well as the metabolism of xenobiotics. For example, CYP2B4 metabolizes substituted amines, CYP2E1 metabolizes various alcohols and halogenated alkenes, and CYP1A2 catalyzes the oxygenation of aromatic compounds and polycyclic hydrocarbons. 4-phenyl-1,2,3-Thiadiazole is, at 100 μM, a selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1), but not others (CYP1A2), with inactivation occurring in a mechanism-based manner. 1,2,3-Thiadiazole compounds and their derivatives, including 4-phenyl-1,2,3-thiadiazole, are also commonly used as fungicides, herbicides, and plant growth regulators.
Chemical PropertiesOff-white to light brown solid
Synthesis Reference(s)Journal of Medicinal Chemistry, 28, p. 442, 1985 DOI: 10.1021/jm00382a009
Tag:4-PHENYL-1,2,3-THIADIAZOLE(25445-77-6) Related Product Information
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