- Benserazide hydrochloride
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- $0.00 / 1KG
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2024-12-12
- CAS:14919-77-8
- Min. Order: 1KG
- Purity: 98.5%~101.0%,EP
- Supply Ability: 800kg/month
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| | Benserazide hydrochloride Basic information |
| Product Name: | Benserazide hydrochloride | | Synonyms: | RO 4-4602;BENSERAZIDE HYDROCHLORIDE;DL-SERINE 2[(2,3,4-TRIHYDROXYPHENYL)-METHYL] HYDRAZIDE HYDROCHLORIDE;DL-SERINE 2-[(2,3,4-TRIHYDROXYPHENYL)METHYL]HYDRAZIDE HCL;2'-(2,3,4-trihydroxybenzyl)-dl-serinohydrazide monohydrochloride;2-(2,3,4-trihydroxybenzyl)hydrazide,monohydrochloride,dl-serin;dl-serine,2-((2,3,4-trihydroxyphenyl)methyl)hydrazide,monohydrochloride;dl-serine2-(2,3,4-trihydroxybenzyl)hydrazinehydrochloride | | CAS: | 14919-77-8 | | MF: | C10H16ClN3O5 | | MW: | 293.7 | | EINECS: | 238-991-9 | | Product Categories: | Serazide;Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;L-Aromatic Amino Acid Decarboxylase;API;Drug bulk;14919-77-8 | | Mol File: | 14919-77-8.mol |  |
| | Benserazide hydrochloride Chemical Properties |
| Melting point | 146°C | | storage temp. | 2-8°C | | solubility | H2O: 10 mg/mL | | form | solid | | color | White to Off-White | | PH | pH(10g/L, 25℃) : 4.0～5.0 | | Water Solubility | Soluble in water, dimethyl sulfoxide and methanol. Insoluble in ethanol and acetone. | | Sensitive | Light Sensitive | | λmax | 272nm(HCl aq.)(lit.) | | Merck | 14,1050 | | InChIKey | ULFCBIUXQQYDEI-UHFFFAOYSA-N | | CAS DataBase Reference | 14919-77-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 2 | | RTECS | VT9632300 | | HS Code | 29280000 |
| | Benserazide hydrochloride Usage And Synthesis |
| Description | Benserazide is an inhibitor of aromatic L-amino acid decarboxylase (AADC), an enzyme that has dopamine decarboxylase activity. It is also unable to cross the blood-brain barrier. As a result, benserazide blocks the conversion of L-DOPA to dopamine by AADC in the peripheral circulatory system. Benserazide is often combined with L-DOPA in patients with Parkinson’s disease. | | Chemical Properties | White Crystalline Solid | | Uses | Used as antiparkinsonian. A peripheral decarboxylase inhibitor | | Uses | Antiparkinsonian;DOPA decarboxylase inhibitor | | Uses | Inhibitor of L-aromatic amino acid decarboxylaseBenserazide hydrochloride is used as an antiparkinsonian. It is a peripheral decarboxylase inhibitor. It is used as an inhibitor for aromatic L-aminoacid decarboxylase. Further, it serves as an inhibitor of tyrosine hydroxylase (TH) and Tryptophan hydroxylase (TPH) inhibitor. | | Definition | ChEBI: A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of park
nsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions whe
given alone. | | General Description | Benserazide is a peripheral decarboxylase inhibitor. | | Biochem/physiol Actions | Inhibitor of L-aromatic amino acid decarboxylase. |
| | Benserazide hydrochloride Preparation Products And Raw materials |
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