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N6-CYCLOHEXYLADENOSINE

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Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: CAS:36396-99-3
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Nanjing Baifuli Technology Co., Ltd.
Tel: +86-15335185688
Email: sales@unisyn.cn
Products Intro: Product Name:N6-Cyclohexyladenosine
CAS:36396-99-3
Purity:98% Package:On Request
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:N6-Cyclohexyladenosine；CHA
CAS:36396-99-3
Purity:98.00% Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；25 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: NewCan Biotech Limited
Tel: +86-0571-86912261 +8613735419629
Email: sales@newcanbio.com
Products Intro: Product Name:(2R,3R,4S,5R)-2-(6-(Cyclohexylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS:36396-99-3
Purity:97% Package:mgs,gs,kgs
Company Name: Aladdin Scientific
Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:N6-Cyclohexyladenosine
CAS:36396-99-3
Purity:98% Package:$69.9/50mg;$189.9/250mg;$499.9/1g;Bulk package Remarks:98%
N6-CYCLOHEXYLADENOSINE Basic information
Product Name:N6-CYCLOHEXYLADENOSINE
Synonyms:CHA;N6-CYCLOHEXYLADENOSINE;N6-CYCLOHEXYLADENOSINE (CHA) SELECTIVE A 1 ADENOSIN;N(sup 6)-cyclohexyladenosine;Cyclohexyladenosine;N-Cyclohexyladenosine;Adenosine, N-cyclohexyl-;N6-Cyclohexyladenosine,CHA
CAS:36396-99-3
MF:C16H23N5O4
MW:349.38
EINECS:
Product Categories:
Mol File:36396-99-3.mol
N6-CYCLOHEXYLADENOSINE Structure
N6-CYCLOHEXYLADENOSINE Chemical Properties
Melting point 182 - 184°C
Boiling point 675.2±65.0 °C(Predicted)
density 1.71±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form Solid
pka13.12±0.70(Predicted)
color White to Off-White
Stability:Hygroscopic
Safety Information
WGK Germany 3
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
N6-CYCLOHEXYLADENOSINE Usage And Synthesis
DescriptionN6-Cyclohexyladenosine is an adenosine receptor agonist. It selectively binds to adenosine A1 receptors in rat cortical membranes (IC50 = 2.3 nM) over A2 receptors in rat striatal membranes (IC50 = 870 nM). N6-Cyclohexyladenosine decreases heart rate and increases coronary flow in a perfused working rat heart model ex vivo (EC25s = 5 and 860 nM, respectively). In vivo, it decreases heart rate and blood pressure in normotensive rats (EC25s = 2.4 and 4.2 μg/kg, respectively). N6-Cyclohexyladenosine (100 μM) induces sleep in rats when administered via basal forebrain infusion. N6-Cyclohexyladenosine also decreases locomotor activity in mice (ED50 = 60 μg/kg, i.p.).
UsesN6-Cyclohexyladenosine is a derivative of Adenosine (A280400), and is used testing adenosine A1 and A2A receptor activation for pharmaceuticals such as antidepressants. N6-Cyclohexyladenosine also is used as a JAK2 inhibitor, blocking STAT3 signalling in human cancer cells.
Biochem/physiol ActionsSelective A1 adenosine receptor agonist.
storageStore at -20°C
Tag:N6-CYCLOHEXYLADENOSINE(36396-99-3) Related Product Information
Tetramethylthiuram Disulfide Vulcanization accelerator 2',3'-dideoxy-N(6)-cyclohexyladenosine ferritin-cyclohexyladenosine N-ALLYL-N-CYCLOHEXYLADENOSINE N(6)-allyl-N(6)-cyclohexyladenosine (2S)-N6-[2-ENDO-NORBORNYL]ADENOSINE N6-METHYL-2'-DEOXY-ADENOSINE SDZWAG994 CYCLOHEXYLADENOSINE, N6-[ADENINE-2,8-3H]-,N 6-CYCLOHEXYLADENOSINE-[2,8-3H] 6-(METHYLAMINO)PURINE 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE 6-N-HEXYLAMINOPURINE N6-CYCLOHEXYLADENOSINE