ent-8-iso-15(S)-Prostaglandin F2α manufacturers
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| | ent-8-iso-15(S)-Prostaglandin F2α Basic information |
| Product Name: | ent-8-iso-15(S)-Prostaglandin F2α | | Synonyms: | ent-8-iso-15(S)-Prostaglandin F2α;PXGPLTODNUVGFL-XNTKLVSTSA-N;ent-8-iso-15(R)-Prostaglandin F2.alpha.;Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9β,11β,12α,13E,15S)-;ent-8-iso-15(S)-Prostaglandin F-2α,ent8iso15(S)Prostaglandin F2α,ent 8 iso 15(S) Prostaglandin F2α;ent-8-iso-15(S)-Prostaglandin F2α | | CAS: | 214748-66-0 | | MF: | C20H34O5 | | MW: | 354.48 | | EINECS: | | | Product Categories: | | | Mol File: | 214748-66-0.mol |  |
| | ent-8-iso-15(S)-Prostaglandin F2α Chemical Properties |
| storage temp. | Store at -20°C | | solubility | 10 mM Na2CO3: >6.5 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS (pH 7.2): >10 mg/ml |
| | ent-8-iso-15(S)-Prostaglandin F2α Usage And Synthesis |
| Description | Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay. | | Uses | Ent-8-Iso-15(S)-prostaglandin F2α is an isomer of 8-Isoprostaglandin F2α, with a better inhibiting activity in the whole blood platelet aggregation inhibition assay[1]. | | References | [1] Manami S, et al. Selective Synthesis of ent-15-epi-F 2t -Isoprostane and a Deuterated Derivative, Synthesis 2007(15): 2397-2403. |
| | ent-8-iso-15(S)-Prostaglandin F2α Preparation Products And Raw materials |
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