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cefsulodin sodium salt

cefsulodin sodium salt Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Cefsulodine sodium
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:52152-93-9
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: career henan chemical co
Tel: +86-371-86658258
Products Intro: Product Name:Cefsulodine sodium
Purity:99% Package:1KG;100USD
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Products Intro: Product Name:Cefsulodin Sodium Salt
Purity:99% Package:5KG;1KG Remarks:C22H19N4NaO8S2
Company Name: Haihang Industry Co.,Ltd
Tel: 86-531-88032799
Products Intro: CAS:52152-93-9

Lastest Price from cefsulodin sodium salt manufacturers

  • Cefsulodine sodium
  • US $0.01-1.00 / KG
  • 2020-05-09
  • CAS:52152-93-9
  • Min. Order: 25KG
  • Purity: 99%min
  • Supply Ability: 20 tons
  • Cefsulodine sodium
  • US $100.00 / KG
  • 2019-07-06
  • CAS:52152-93-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: Customized
cefsulodin sodium salt Basic information
Cephalosporins Category Toxicity grading Acute toxicity Flammability and hazard characteristics Storage Characteristics Extinguishing agent
Product Name:cefsulodin sodium salt
Synonyms:pseudocef;pseudomonil;pyocefal;pyridinium,4-(aminocarbonyl)-1-[[(6r,7r)-2-carboxy-8-oxo-7-[[(2r)-phenylsulfoa;sce129;sulcephalosporin;takesulin;Sodium (6R,7R)-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[[(2R)-2-phenyl-2-sulfonatoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Product Categories:GUBERNAL;antibiotic;A - KResearch Essentials;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;AntibioticsAntibiotics;Chemical Structure Class;Core Bioreagents;Interferes with Cell Wall SynthesisAntibiotics;Mechanism of Action;Penicillins and Cephalosporins (beta-Lactams);Spectrum of Activity
Mol File:52152-93-9.mol
cefsulodin sodium salt Structure
cefsulodin sodium salt Chemical Properties
Melting point 175 C
storage temp. 2-8°C
solubility H2O: 50 mg/mL, clear, light yellow
form powder or crystals
Water Solubility Soluble in water.
Merck 13,1958
EPA Substance Registry SystemPyridinium, 4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-phenylsulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, monosodium salt (52152-93-9)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-42/43-20/21/22
Safety Statements 22-26-36/37-45-36
WGK Germany 2
RTECS UU1785000
HS Code 29419059
ToxicityLD50 in mice (mg/kg): >4000 i.p.; >15000 orally (Bryskier)
MSDS Information
cefsulodin sodium salt Usage And Synthesis
CephalosporinsCefsulodine sodium is a cephalosporin antibiotic, its antimicrobial spectrum is narrow, because it has good permeability to the outer layer of the cell wall of Pseudomonas aeruginosa , and it has a high affinity on penicillin-binding protein LA, LB and Ⅲ and thus it has strong bactericidal inhibition effect on the formation of the cell wall peptidoglycan , it has a strong and specific bactericidal effect on P. aeruginosa , the MIC is 1.5μg/ml, and it has high stability on β-lactamase produced by itself . Its antimicrobial activity against Pseudomonas aeruginosa is stronger than cefoperazone, methyl benzyl amoxicillin (10 times), carbenicillin, piperacillin and hydroxyl ampicillin (16 to 32-fold) , and its antimicrobial activity against Pseudomonas aeruginosa is equal to aminoglycoside antibiotics such as gentamicin, dibekacin . And there is no cross-resistance.After intramuscular or intravenous administration 0.5g, 15min respectively ,it achieves the maximum blood concentration of 37.2μg/ml, and the concentration of the drug increases with the increase of the dose . It can be quickly distributed to the kidneys, blood plasma, lung, heart, digestive tract, liver and spleen, and it can go access to sputum, wound exudate, amniotic fluid and breast milk. PBP is 70%, t1/2 is 1.5h, it is mainly excreted in the urine, 6h after treatment the urine excretion rate is 60% to 70%, metabolites with antibacterial activity are not found in the urine . In renal dysfunction patients , plasma concentration increases, half-life extends and urinary excretion rate decreases.
Sodium cefsulodin is clinically used for the treatment of respiratory tract infections caused by Pseudomonas aeruginosa, pyelonephritis, cystitis, peritonitis, septicemia, prostatitis, burns, wounds and otitis media secondary infection, corneal ulcers, especially penicillin and aminoglycosides antibiotic treatment ineffective Pseudomonas aeruginosa infection.
Adverse reactions occurring rate is approximately 1.3%, it is similar to other cephalosporins. Occasionally allergic reactions occur, such as rash, urticaria.There are gastrointestinal reactions. Injection site is painful, intravenous injection causes phlebitis, mildly elevated serum transaminases , few visible proteinuria; there are also visible thrombocytopenia, increased eosinophils; rare thrombocytopenia, vitamin deficiency and the like.
Patients allergic to the chemicalsare are banned .Patients allergic to penicillin,and cephalosporin , having history of allergy diseases, allergic bodies, severe renal dysfunction, and pregnant women should use with caution. Cefsulodine sodium together with diuretics, aminoglycosides can increase renal toxicity. Check liver function, kidney function and blood at regular intervals .
The above information is edited by the chemicalbook of Tian Ye.
CategoryToxic substances
Toxicity gradingLow toxicity
Acute toxicityIntravenous-rat LD50: 3030 mg/kg; Intravenous-Mouse LD50: 3780 mg/kg.
Flammability and hazard characteristicsThermal decomposition produces toxic nitrogen oxides, sulfur oxides, sodium oxide fumes.
Storage CharacteristicsVentilated, low-temperature ,dry storeroom.
Extinguishing agentWater, carbon dioxide, foam, powder.
Usesbetaadrenergic blocker
UsesCefsulodin is a third generation cephalosporin (C258750) antibiotic designed specifically for Pseudomonas Aeruginosa.
UsesA β lactam antibiotic.
Brand nameCefomonil (TAP).
cefsulodin sodium salt Preparation Products And Raw materials
Tag:cefsulodin sodium salt(52152-93-9) Related Product Information
(6R,7R)-3-[(4-Carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sulfamethazine sodium salt Sodium formate Sodium sodium 2-[(2-aminoethyl)amino]ethanesulphonate N-(Carbamoylmethyl)taurine cefsulodin sodium salt