N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide
| 中文名称 | N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide |
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| 中文同义词 | N-[(4,6-二甲基-2-氧代-1H-吡啶-3-基)甲基]-5-乙基-6-[乙基(四氢吡喃-4-基)氨基]-2-(1-哌啶基甲基) 苯并呋喃-4-羧酰胺;化合物 EZH2-IN-15;N-((4,6-二甲基-2-氧代-1,2-二氢吡啶-3-基)甲基)-5-乙基-6-(乙基(四氢-2H-吡喃-4-基)氨基)-2-(哌啶-1-基甲基)苯并呋喃-4-甲酰胺 |
| 英文名称 | N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide |
| 英文同义词 | 4-Benzofurancarboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-ethyl-6-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-2-(1-piperidinylmethyl)-;N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide;EZH2-IN-15 |
| CAS号 | 2098545-98-1 |
| 分子式 | C32H44N4O4 |
| 分子量 | 548.72 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 2098545-98-1.mol |
| 结构式 | ![N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide 结构式](CAS/20210111/GIF/2098545-98-1.gif) |
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide 性质
| 沸点 | 735.3±60.0 °C(Predicted) |
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| 密度 | 1.168±0.06 g/cm3(Predicted) |
| 酸度系数(pKa) | 14.01±0.46(Predicted) |
| 形态 | 固体 |
| 颜色 | 米白色至黄色 |
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide 用途与合成方法
EZH2-IN-15 是一个 EZH2 抑制剂。EZH2-IN-15 具有抗肿瘤活性，可用于 H3K27me3 依赖性肿瘤的研究。