| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Bucumarol (HCl);Bucumarol (HCl)
CAS:36556-75-9
Purity:98% Package:5 mg
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| | bucumolol hydrochloride Basic information |
| Product Name: | bucumolol hydrochloride | | Synonyms: | bucumolol hydrochloride;Bucumalol;(+-)-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride;8-(2-Hydroxy-3-tert-butylaminopropoxy)-5-methylcoumarin hydrochloride;Bucumarol;CS 359;DL-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride;dl-Bucumolol hydrochloride | | CAS: | 36556-75-9 | | MF: | C17H23NO4.ClH | | MW: | 341.833 | | EINECS: | | | Product Categories: | | | Mol File: | 36556-75-9.mol |  |
| | bucumolol hydrochloride Chemical Properties |
| Melting point | 226-228° (dec) |
| Toxicity | LD50 in male, female mice (mg/kg): 676, 692 orally; 33.1, 31.6 i.v. (Oshima) |
| | bucumolol hydrochloride Usage And Synthesis |
| Originator | Bucumarol,Sankyo,Japan,1982 | | Definition | ChEBI: Bucumolol hydrochloride is a member of coumarins. | | Manufacturing Process | A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g
of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for
15 hours. The reaction mixture is concentrated under reduced pressure to
dryness. The residue is recrystallized from a mixture of ethanol and ether to
give 2.1 g of the desired product melting at 226° to 228°C (with
decomposition).
In practice it is usually used as hydrochloride. | | Therapeutic Function | Beta-adrenergic blocker |
| | bucumolol hydrochloride Preparation Products And Raw materials |
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