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| | 2,3-dihydro-6,7-dimethyl-2-thioxo-1H-pteridin-4-one Basic information |
| Product Name: | 2,3-dihydro-6,7-dimethyl-2-thioxo-1H-pteridin-4-one | | Synonyms: | 2,3-dihydro-6,7-dimethyl-2-thioxo-1H-pteridin-4-one;2,3-Dihydro-6,7-dimethyl-2-thioxo-4(1H)-pteridinone;4(1H)-Pteridinone, 2,3-dihydro-6,7-dimethyl-2-thioxo-;6,7-Dimethyl-2-thioxo-2,3-dihydropteridin-4(1H)-one;6,7-Dimethyl-2-thioxo-2,3-dihydropteridin-4(8H)-one;6,7-dimethyl-2-thioxo-2,8-dihydropteridin-4(3H)-one;HIV-1 integrase inhibitor 11 | | CAS: | 54030-51-2 | | MF: | C8H8N4OS | | MW: | 208.24 | | EINECS: | 2589320 | | Product Categories: | | | Mol File: | 54030-51-2.mol |  |
| | 2,3-dihydro-6,7-dimethyl-2-thioxo-1H-pteridin-4-one Chemical Properties |
| solubility | DMSO (Sparingly), Methanol (Slightly) | | form | Solid | | color | Beige |
| | 2,3-dihydro-6,7-dimethyl-2-thioxo-1H-pteridin-4-one Usage And Synthesis |
| Uses | HIV-1 integrase inhibitor 11 (compound 5) is a potent inhibitor of HIV-1 integrase, with the IC50 of 125 μM[1]. | | References | [1] Hardik Bhatt, et al. Discovery of HIV-1 integrase inhibitors: pharmacophore mapping, virtual screening, molecular docking, synthesis, and biological evaluation. Chem Biol Drug Des. 2014 Feb;83(2):154-66. DOI:10.1111/cbdd.12207 |
| | 2,3-dihydro-6,7-dimethyl-2-thioxo-1H-pteridin-4-one Preparation Products And Raw materials |
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