LEUCOSCEPTOSIDEA manufacturers
- Leucosceptoside A
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2023-02-24
- CAS:83529-62-8
- Min. Order: 5mg
- Purity: ≥95%(HPLC)
- Supply Ability: 10 g
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| | LEUCOSCEPTOSIDEA Basic information |
| Product Name: | LEUCOSCEPTOSIDEA | | Synonyms: | LEUCOSCEPTOSIDEA;2-(3,4-Dihydroxyphenyl)ethyl 3-O-(α-L-rhamnopyranosyl)-4-O-[(E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl]-β-D-glucopyranoside;3,4-Dihydroxyphenethyl 3-O-α-L-rhamnopyranosyl-4-O-(4-hydroxy-3-methoxycinnamoyl)-β-D-glucopyranoside;β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate] | | CAS: | 83529-62-8 | | MF: | C30H38O15 | | MW: | 638.61 | | EINECS: | | | Product Categories: | | | Mol File: | 83529-62-8.mol |  |
| | LEUCOSCEPTOSIDEA Chemical Properties |
| Boiling point | 884.547±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.545±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 9.728±0.31(predicted) |
| | LEUCOSCEPTOSIDEA Usage And Synthesis |
| Uses | Leucosceptoside A is a phenylethanoid glycoside with anti-hyperglycemic and anti-hypertensive activities. Leucosceptoside A shows inhibitory activity against α-glucosidase and PKCα (IC50 of 19.0 μM)[1][2][3]. | | IC 50 | PKCα: 19 μM (IC50) | | References | [1] Chika Ifeanyi Chukwuma, et al. Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review. J Ethnopharmacol. 2019 May 10;235:329-360. DOI:10.1016/j.jep.2019.02.024
[2] Yan-Yun Li, et al. Pedicularioside A from Buddleia lindleyana inhibits cell death induced by 1-methyl-4-phenylpyridinium ions (MPP+) in primary cultures of rat mesencephalic neurons. Eur J Pharmacol. 2008 Jan 28;579(1-3):134-40. DOI:10.1016/j.ejphar.2007.10.052
[3] B N Zhou, et al. Phenylethanoid glycosides from Digitalis purpurea and Penstemon linarioides with PKCalpha-inhibitory activity. J Nat Prod. 1998 Nov;61(11):1410-2. DOI:10.1021/np980147s |
| | LEUCOSCEPTOSIDEA Preparation Products And Raw materials |
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