| Company Name: |
INTATRADE GmbH |
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- L-Kynurenine
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- $56.00
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2026-09-11
- CAS:2922-83-0
- Purity: 99.88%
- Supply Ability: 10g
- L-kynurenine
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- $15.00
-
2021-07-02
- CAS:2922-83-0
- Min. Order: 1KG
- Purity: 99%+ HPLC
- L-KYNURENINE
-
- $7.00
-
2019-12-31
- CAS:2922-83-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
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| | L-KYNURENINE Basic information |
| | L-KYNURENINE Chemical Properties |
| Melting point | 219 °C | | Boiling point | 466.6±45.0 °C(Predicted) | | density | 1.343±0.06 g/cm3(Predicted) | | refractive index | -33 ° (C=0.4, H2O) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml). | | form | crystalline | | pka | 2.21±0.23(Predicted) | | color | light yellow | | Optical Rotation | -30.525 (H2O) | | Merck | 14,5328 | | Stability: | Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months. | | Major Application | detection | | InChI | InChI=1/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/s3 | | InChIKey | YGPSJZOEDVAXAB-QMMMGPOBSA-N | | SMILES | C1(C=CC=CC=1N)C(=O)C[C@H](N)C(=O)O |&1:10,r| | | CAS DataBase Reference | 2922-83-0(CAS DataBase Reference) |
| WGK Germany | 3 | | RTECS | CY9049700 | | HS Code | 2922500090 | | Storage Class | 11 - Combustible Solids |
| | L-KYNURENINE Usage And Synthesis |
| Description | Kynurenine (2922-83-0) is a tryptophan catabolite.1Endogenous tumor-promoting ligand of the human aryl hydrocarbon receptor (AhR). Constitutively generated by human tumor cells via the action of the tryptophan degrading enzyme, tryptophan-2,3-dioxygenase (TDO). Kynurenine suppresses antitumor immune responses and promotes tumor cell survival and motility.2 | | Uses | L-Kynurenine has been used as a standard for indoleamine-2,3-dioxygenase (IDO) assay. It has also been used as a standard to extract and quantify kynurenine from cultured cells and media. | | Definition | ChEBI: A kynurenine that has L configuration. | | Biochem/physiol Actions | Key intermediate in the breakdown pathway of tryptophan. | | storage | Store at RT | | References | [1] JOYCE A IBANA. Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced Chlamydia trachomatis persistence in human epithelial cells.[J]. Infection and Immunity, 2011: 4425-4437. DOI:10.1128/iai.05659-11
[2] CHRISTIANE A. OPITZ. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor[J]. Nature, 2011, 478 7368: 197-203. DOI:10.1038/nature10491 |
| | L-KYNURENINE Preparation Products And Raw materials |
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