| Company Name: |
BOC Sciences
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| Tel: |
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| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:D-NMAPPD
CAS:35922-06-6
Purity:≥98% Remarks:D-NMAPPD is an inhibitor of ceramidase. It induces cell death in SW403 colon adenocarcinoma cells in a time- and concentration-dependent manner but doesn't have effect on viability of rat hepatocytes
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:D-NMAPPD
CAS:35922-06-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:(1R,2R)-B13
CAS:35922-06-6
Purity:98% Package:5mg; 50mg; 10mg Remarks:Medbio
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:D-NMAPPD
CAS:35922-06-6
Purity:NULL Package:1mg;2.5mg Remarks:NULL
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(1R,2R)-B13 manufacturers
- D-NMAPPD
-
- $105.00 / 1mg
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2025-08-29
- CAS:35922-06-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | (1R,2R)-B13 Basic information |
| Product Name: | (1R,2R)-B13 | | Synonyms: | (1R,2R)-B13;D-NMAPPD Exclusive;N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]-TETRADECANAMIDE;D-NMAPPD;CAY10466;Tetradecanamide, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]- | | CAS: | 35922-06-6 | | MF: | C23H38N2O5 | | MW: | 422.56 | | EINECS: | | | Product Categories: | | | Mol File: | 35922-06-6.mol |  |
| | (1R,2R)-B13 Chemical Properties |
| Boiling point | 636.2±55.0 °C(Predicted) | | density | 1.101±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:2): .3 mg/ml | | form | A crystalline solid | | pka | 12.72±0.20(Predicted) | | color | white to beige | | Optical Rotation | [α]/D -28 to -34, c =0.1 in chloroform-d |
| | (1R,2R)-B13 Usage And Synthesis |
| Uses | D-NMAPPD is d-NMAPPD is a potent Acid Ceramidase inhibitor that induces apoptosis.. | | Biological Activity | D-NMAPPD (B13), a myristoyl-CoA analog, is a cell penetrant inhibitor of N-myristoyltransferases th at suppressed FRS2α (fibroblast growth factor receptor substrate 2) myristoylation. D-NMAPPD inhibits wild-type FGFRs and drug-resistant mutants (FGFRsDRM) oncogenic signaling in cancer cells. D-NMAPPD potently inhibits growth of xenograft tumors in mice. D-NMAPPD is a potent inhibitor of ceramidase th at elevates endogenous ceramide levels and suppress growth of cancer cells. |
| | (1R,2R)-B13 Preparation Products And Raw materials |
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